Influenza B virus triggering macrophage activation syndrome in an infant

K. Jayashree, Suchetha Rao, Nutan Kamath

Research output: Contribution to journalArticle

Abstract

Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.

Original languageEnglish
Pages (from-to)802-803
Number of pages2
JournalIndian Journal of Critical Care Medicine
Volume21
Issue number11
DOIs
Publication statusPublished - 01-11-2017

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Macrophage Activation Syndrome
Influenza B virus
Febrile Seizures
Macrophage Activation
Hypertriglyceridemia
Blood Sedimentation
Immunoglobulins
Liver Diseases
Steroids
T-Lymphocytes
Liver
Enzymes
Infection
Therapeutics

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Cite this

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Influenza B virus triggering macrophage activation syndrome in an infant. / Jayashree, K.; Rao, Suchetha; Kamath, Nutan.

In: Indian Journal of Critical Care Medicine, Vol. 21, No. 11, 01.11.2017, p. 802-803.

Research output: Contribution to journalArticle

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