Abstract
Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.
| Original language | English |
|---|---|
| Pages (from-to) | 802-803 |
| Number of pages | 2 |
| Journal | Indian Journal of Critical Care Medicine |
| Volume | 21 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 01-11-2017 |
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All Science Journal Classification (ASJC) codes
- Critical Care and Intensive Care Medicine
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Influenza B virus triggering macrophage activation syndrome in an infant. / Jayashree, K.; Rao, Suchetha; Kamath, Nutan.
In: Indian Journal of Critical Care Medicine, Vol. 21, No. 11, 01.11.2017, p. 802-803.Research output: Contribution to journal › Article
TY - JOUR
T1 - Influenza B virus triggering macrophage activation syndrome in an infant
AU - Jayashree, K.
AU - Rao, Suchetha
AU - Kamath, Nutan
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.
AB - Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.
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UR - http://www.scopus.com/inward/citedby.url?scp=85034614009&partnerID=8YFLogxK
U2 - 10.4103/0972-5229.218137
DO - 10.4103/0972-5229.218137
M3 - Article
VL - 21
SP - 802
EP - 803
JO - Indian Journal of Critical Care Medicine
JF - Indian Journal of Critical Care Medicine
SN - 0972-5229
IS - 11
ER -