Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids

M.K. Unnikrishnan, M.N.A. Rao

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Curcumin, demethoxy curcumin, bis demethoxy curcumin and diacetyl curcumin inhibited nitrite induced oxidation of hemoglobin in both erythrocytes and purified human hemoglobin. The activities of all the compounds except diacetyl curcumin were similar suggesting that the methoxy substituents have very little role in this biological activity. Acetylation of phenolic groups resulted in significant reduction of activity.
Original languageUndefined/Unknown
Pages (from-to)490-492
Number of pages3
JournalPharmazie
Volume50
Issue number7
Publication statusPublished - 1995

Cite this

Unnikrishnan, M. K., & Rao, M. N. A. (1995). Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids. Pharmazie, 50(7), 490-492.
Unnikrishnan, M.K. ; Rao, M.N.A. / Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids. In: Pharmazie. 1995 ; Vol. 50, No. 7. pp. 490-492.
@article{d42afa148cb44ed2be85b12499abce15,
title = "Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids",
abstract = "Curcumin, demethoxy curcumin, bis demethoxy curcumin and diacetyl curcumin inhibited nitrite induced oxidation of hemoglobin in both erythrocytes and purified human hemoglobin. The activities of all the compounds except diacetyl curcumin were similar suggesting that the methoxy substituents have very little role in this biological activity. Acetylation of phenolic groups resulted in significant reduction of activity.",
author = "M.K. Unnikrishnan and M.N.A. Rao",
note = "cited By 44",
year = "1995",
language = "Undefined/Unknown",
volume = "50",
pages = "490--492",
journal = "Die Pharmazie",
issn = "0031-7144",
publisher = "Govi-Verlag Pharmazeutischer Verlag GmbH",
number = "7",

}

Unnikrishnan, MK & Rao, MNA 1995, 'Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids', Pharmazie, vol. 50, no. 7, pp. 490-492.

Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids. / Unnikrishnan, M.K.; Rao, M.N.A.

In: Pharmazie, Vol. 50, No. 7, 1995, p. 490-492.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Inhibition of nitrite induced oxidation of hemoglobin by curcuminoids

AU - Unnikrishnan, M.K.

AU - Rao, M.N.A.

N1 - cited By 44

PY - 1995

Y1 - 1995

N2 - Curcumin, demethoxy curcumin, bis demethoxy curcumin and diacetyl curcumin inhibited nitrite induced oxidation of hemoglobin in both erythrocytes and purified human hemoglobin. The activities of all the compounds except diacetyl curcumin were similar suggesting that the methoxy substituents have very little role in this biological activity. Acetylation of phenolic groups resulted in significant reduction of activity.

AB - Curcumin, demethoxy curcumin, bis demethoxy curcumin and diacetyl curcumin inhibited nitrite induced oxidation of hemoglobin in both erythrocytes and purified human hemoglobin. The activities of all the compounds except diacetyl curcumin were similar suggesting that the methoxy substituents have very little role in this biological activity. Acetylation of phenolic groups resulted in significant reduction of activity.

M3 - Article

VL - 50

SP - 490

EP - 492

JO - Die Pharmazie

JF - Die Pharmazie

SN - 0031-7144

IS - 7

ER -