Inhibition of radiation-induced lipid peroxidation by curcumin

N. Sreejayan, M.N.A. Rao, K.I. Priyadarsini, T.P.A. Devasagayam

Research output: Contribution to journalArticle

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Abstract

The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.
Original languageUndefined/Unknown
Pages (from-to)127-130
Number of pages4
JournalInternational Journal of Pharmaceutics
Volume151
Issue number1
DOIs
Publication statusPublished - 1997

Cite this

Sreejayan, N., Rao, M. N. A., Priyadarsini, K. I., & Devasagayam, T. P. A. (1997). Inhibition of radiation-induced lipid peroxidation by curcumin. International Journal of Pharmaceutics, 151(1), 127-130. https://doi.org/10.1016/S0378-5173(97)04900-4
Sreejayan, N. ; Rao, M.N.A. ; Priyadarsini, K.I. ; Devasagayam, T.P.A. / Inhibition of radiation-induced lipid peroxidation by curcumin. In: International Journal of Pharmaceutics. 1997 ; Vol. 151, No. 1. pp. 127-130.
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Sreejayan, N, Rao, MNA, Priyadarsini, KI & Devasagayam, TPA 1997, 'Inhibition of radiation-induced lipid peroxidation by curcumin', International Journal of Pharmaceutics, vol. 151, no. 1, pp. 127-130. https://doi.org/10.1016/S0378-5173(97)04900-4

Inhibition of radiation-induced lipid peroxidation by curcumin. / Sreejayan, N.; Rao, M.N.A.; Priyadarsini, K.I.; Devasagayam, T.P.A.

In: International Journal of Pharmaceutics, Vol. 151, No. 1, 1997, p. 127-130.

Research output: Contribution to journalArticle

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T1 - Inhibition of radiation-induced lipid peroxidation by curcumin

AU - Sreejayan, N.

AU - Rao, M.N.A.

AU - Priyadarsini, K.I.

AU - Devasagayam, T.P.A.

N1 - cited By 63

PY - 1997

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AB - The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.

U2 - 10.1016/S0378-5173(97)04900-4

DO - 10.1016/S0378-5173(97)04900-4

M3 - Article

VL - 151

SP - 127

EP - 130

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

SN - 0378-5173

IS - 1

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