The ability of curcumin, a natural antioxidant from turmeric, to inhibit radiation-induced lipid peroxidation in rat liver microsomes was examined. Curcumin was incorporated into microsomes during ultracentrifugation. The antioxidant has significant time- and concentration-dependent inhibitory effect on lipid peroxidation induced by τ-radiation. Inhibition of lipid peroxidation was also observed in microsomes samples previously saturated with N2O.
|Number of pages||4|
|Journal||International Journal of Pharmaceutics|
|Publication status||Published - 1997|