Inter-relationship between rheumatoid arthritis and periodontitis

J. Rajkarnikar, B. S. Thomas, S. K. Rao

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background Periodontal medicine defines a rapidly emerging branch of Periodontology focusing on establishing a strong relationship between periodontal health and systemic health. It is speculated that the major common dysregulation which links Periodontitis with Rheumatoid arthritis (RA) is being played by the mediators of immune inflammatory response. Objectives To determine whether there is any relationship between periodontal disease and Rheumatoid arthritis. Methods A total of 100 patients were included for the present study which was divided into two groups: one group (cases) included 50 patients attending the Department of Orthopedics, Kasturba Medical College, Manipal who were diagnosed of Rheumatoid arthritis. Another subject population included 50 patients as controls attending the Department of Oral Medicine, Manipal College of Dental Sciences, Manipal with age and gender matched with those of rheumatoid arthritis group. Specific measures for periodontitis included plaque index, gingival index, number of missing teeth, and radiographic alveolar bone loss scores. Measures of rheumatoid arthritis included health assessment questionaires, levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Various periodontal parameters were compared between the cases and controls. Results The average alveolar bone loss was statistically more severe in Rheumatoid arthritis (RA) group than in the controls although there were similar plaque index in both the groups. The gingival index was statistically higher in the RA group. The Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) levels of RA patients were also significantly associated with the severity of periodontal disease. Conclusion There was a significant association between Rheumatoid arthritis and Periodontitis which may be due to a common underlying deregulation of the inflammatory response in these individuals.

Original languageEnglish
Pages (from-to)22-26
Number of pages5
JournalKathmandu University Medical Journal
Volume11
Issue number41
Publication statusPublished - 01-01-2013
Externally publishedYes

Fingerprint

Periodontitis
Rheumatoid Arthritis
Alveolar Bone Loss
Periodontal Index
Blood Sedimentation
Periodontal Diseases
C-Reactive Protein
Tooth
Health
Periodontics
Oral Medicine
Orthopedics
Control Groups

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Rajkarnikar, J., Thomas, B. S., & Rao, S. K. (2013). Inter-relationship between rheumatoid arthritis and periodontitis. Kathmandu University Medical Journal, 11(41), 22-26.
Rajkarnikar, J. ; Thomas, B. S. ; Rao, S. K. / Inter-relationship between rheumatoid arthritis and periodontitis. In: Kathmandu University Medical Journal. 2013 ; Vol. 11, No. 41. pp. 22-26.
@article{c3eee4690d9145beb060e278de038631,
title = "Inter-relationship between rheumatoid arthritis and periodontitis",
abstract = "Background Periodontal medicine defines a rapidly emerging branch of Periodontology focusing on establishing a strong relationship between periodontal health and systemic health. It is speculated that the major common dysregulation which links Periodontitis with Rheumatoid arthritis (RA) is being played by the mediators of immune inflammatory response. Objectives To determine whether there is any relationship between periodontal disease and Rheumatoid arthritis. Methods A total of 100 patients were included for the present study which was divided into two groups: one group (cases) included 50 patients attending the Department of Orthopedics, Kasturba Medical College, Manipal who were diagnosed of Rheumatoid arthritis. Another subject population included 50 patients as controls attending the Department of Oral Medicine, Manipal College of Dental Sciences, Manipal with age and gender matched with those of rheumatoid arthritis group. Specific measures for periodontitis included plaque index, gingival index, number of missing teeth, and radiographic alveolar bone loss scores. Measures of rheumatoid arthritis included health assessment questionaires, levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Various periodontal parameters were compared between the cases and controls. Results The average alveolar bone loss was statistically more severe in Rheumatoid arthritis (RA) group than in the controls although there were similar plaque index in both the groups. The gingival index was statistically higher in the RA group. The Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) levels of RA patients were also significantly associated with the severity of periodontal disease. Conclusion There was a significant association between Rheumatoid arthritis and Periodontitis which may be due to a common underlying deregulation of the inflammatory response in these individuals.",
author = "J. Rajkarnikar and Thomas, {B. S.} and Rao, {S. K.}",
year = "2013",
month = "1",
day = "1",
language = "English",
volume = "11",
pages = "22--26",
journal = "Kathmandu University Medical Journal",
issn = "1812-2027",
publisher = "Kathmandu University",
number = "41",

}

Rajkarnikar, J, Thomas, BS & Rao, SK 2013, 'Inter-relationship between rheumatoid arthritis and periodontitis', Kathmandu University Medical Journal, vol. 11, no. 41, pp. 22-26.

Inter-relationship between rheumatoid arthritis and periodontitis. / Rajkarnikar, J.; Thomas, B. S.; Rao, S. K.

In: Kathmandu University Medical Journal, Vol. 11, No. 41, 01.01.2013, p. 22-26.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Inter-relationship between rheumatoid arthritis and periodontitis

AU - Rajkarnikar, J.

AU - Thomas, B. S.

AU - Rao, S. K.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Background Periodontal medicine defines a rapidly emerging branch of Periodontology focusing on establishing a strong relationship between periodontal health and systemic health. It is speculated that the major common dysregulation which links Periodontitis with Rheumatoid arthritis (RA) is being played by the mediators of immune inflammatory response. Objectives To determine whether there is any relationship between periodontal disease and Rheumatoid arthritis. Methods A total of 100 patients were included for the present study which was divided into two groups: one group (cases) included 50 patients attending the Department of Orthopedics, Kasturba Medical College, Manipal who were diagnosed of Rheumatoid arthritis. Another subject population included 50 patients as controls attending the Department of Oral Medicine, Manipal College of Dental Sciences, Manipal with age and gender matched with those of rheumatoid arthritis group. Specific measures for periodontitis included plaque index, gingival index, number of missing teeth, and radiographic alveolar bone loss scores. Measures of rheumatoid arthritis included health assessment questionaires, levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Various periodontal parameters were compared between the cases and controls. Results The average alveolar bone loss was statistically more severe in Rheumatoid arthritis (RA) group than in the controls although there were similar plaque index in both the groups. The gingival index was statistically higher in the RA group. The Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) levels of RA patients were also significantly associated with the severity of periodontal disease. Conclusion There was a significant association between Rheumatoid arthritis and Periodontitis which may be due to a common underlying deregulation of the inflammatory response in these individuals.

AB - Background Periodontal medicine defines a rapidly emerging branch of Periodontology focusing on establishing a strong relationship between periodontal health and systemic health. It is speculated that the major common dysregulation which links Periodontitis with Rheumatoid arthritis (RA) is being played by the mediators of immune inflammatory response. Objectives To determine whether there is any relationship between periodontal disease and Rheumatoid arthritis. Methods A total of 100 patients were included for the present study which was divided into two groups: one group (cases) included 50 patients attending the Department of Orthopedics, Kasturba Medical College, Manipal who were diagnosed of Rheumatoid arthritis. Another subject population included 50 patients as controls attending the Department of Oral Medicine, Manipal College of Dental Sciences, Manipal with age and gender matched with those of rheumatoid arthritis group. Specific measures for periodontitis included plaque index, gingival index, number of missing teeth, and radiographic alveolar bone loss scores. Measures of rheumatoid arthritis included health assessment questionaires, levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Various periodontal parameters were compared between the cases and controls. Results The average alveolar bone loss was statistically more severe in Rheumatoid arthritis (RA) group than in the controls although there were similar plaque index in both the groups. The gingival index was statistically higher in the RA group. The Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) levels of RA patients were also significantly associated with the severity of periodontal disease. Conclusion There was a significant association between Rheumatoid arthritis and Periodontitis which may be due to a common underlying deregulation of the inflammatory response in these individuals.

UR - http://www.scopus.com/inward/record.url?scp=84879267499&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879267499&partnerID=8YFLogxK

M3 - Article

C2 - 23774408

AN - SCOPUS:84879267499

VL - 11

SP - 22

EP - 26

JO - Kathmandu University Medical Journal

JF - Kathmandu University Medical Journal

SN - 1812-2027

IS - 41

ER -