Intestinal protozoal infestation profile in persistent diarrhea in children below age 5 years in western Nepal

Chiranjay Mukhopadhyay, G. Wilson, D. Pradhan, P. G. Shivananda

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Unlike acute diarrhea, the role of pathogens in persistent diarrhea in children in Nepal is unclear. Protozoal parasites are suspected to be a major cause. The study was carried out to find the association between protozoal agents and persistent diarrhea in children below age 5 years from western Nepal. Stool samples were collected from 253 children with persistent diarrhea, from 155 children with acute diarrhea (disease controls) and from 100 healthy children from the community (normal controls). Of 253 children with persistent diarrhea, 90 (35.5%) had protozoal infections, 63 (24.9%) helminthic infections, 32 (12.6%) had bacterial infections and 16 had mixed infections. Giardia lamblia was the most prevalent (67.7%), followed by Entamaeba histolytica (27.7%). HIV infection and severe malnutrition were associated with Cyclospora cayetanensis and Cryptosporidium spp causing persistent diarrhea. We conclude that stool microscopy should be routinely performed in children with persistent diarrhea since protozoal infections can be cured with effective treatment and control can be achieved by proper health education.

Original languageEnglish
Pages (from-to)13-19
Number of pages7
JournalSoutheast Asian Journal of Tropical Medicine and Public Health
Volume38
Issue number1
Publication statusPublished - 01-01-2007

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Nepal
Diarrhea
Cyclospora
Infection
Giardia lamblia
Cryptosporidium
Acute Disease
Coinfection
Health Education
Bacterial Infections
Malnutrition
HIV Infections
Microscopy
Parasites

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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abstract = "Unlike acute diarrhea, the role of pathogens in persistent diarrhea in children in Nepal is unclear. Protozoal parasites are suspected to be a major cause. The study was carried out to find the association between protozoal agents and persistent diarrhea in children below age 5 years from western Nepal. Stool samples were collected from 253 children with persistent diarrhea, from 155 children with acute diarrhea (disease controls) and from 100 healthy children from the community (normal controls). Of 253 children with persistent diarrhea, 90 (35.5{\%}) had protozoal infections, 63 (24.9{\%}) helminthic infections, 32 (12.6{\%}) had bacterial infections and 16 had mixed infections. Giardia lamblia was the most prevalent (67.7{\%}), followed by Entamaeba histolytica (27.7{\%}). HIV infection and severe malnutrition were associated with Cyclospora cayetanensis and Cryptosporidium spp causing persistent diarrhea. We conclude that stool microscopy should be routinely performed in children with persistent diarrhea since protozoal infections can be cured with effective treatment and control can be achieved by proper health education.",
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Intestinal protozoal infestation profile in persistent diarrhea in children below age 5 years in western Nepal. / Mukhopadhyay, Chiranjay; Wilson, G.; Pradhan, D.; Shivananda, P. G.

In: Southeast Asian Journal of Tropical Medicine and Public Health, Vol. 38, No. 1, 01.01.2007, p. 13-19.

Research output: Contribution to journalArticle

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