Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries

Abhishek Rao Kordcal, Vijaykumar Tipanna Kalyanappagol, Amrut Krishnananda Rao, Madhu Rao

Research output: Contribution to journalArticle

Abstract

Aims: To compare sensory, motor effects and haemodynamic stability of 2ml intrathecal isobaric ropivacaine (0.75%) with 3ml hyperbaric bupivacaine (0.75%) in patients undergoing endoscopic urological surgery. Study Design: Randomized controlled trial involving 142 patients undergoing transurethral resection of prostate (TURP) and URS (urethroscopy) in a tertiary care hospital, India. Methods and materials: Patients were randomly allocated to, Group 1 (3ml of 0.5% (15mg) hyperbaric bupivacaine) and Group 2 (2ml of 0.75% isobaric ropivacaine(15mg)). Onset and highest level of sensory block, onset and duration of motor block, quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied. Statistical analysis used: Unpaired t-test was used to test continuous variables and chi square test/Fisher’s exact test for categorical variables. Results: The mean of highest sensory block, 2 segment regression of sensory block and time for sensory level to regress below T10 was significantly more in group 1 compared to group 2 (P<0.05). There was a significant delay of mean time to onset of motor block to Bromage score 1 in group 2(P<0.001). The mean duration of complete motor blockade was significantly more in group 1 (P value <0.001). Hypotension was most commonly seen in group 1. Conclusion: Ropivacaine provides comparable quality of sensory block but has slower onset and significantly shorter duration of motor block compared to hyperbaric bupivacaine.

Original languageEnglish
Pages (from-to)127-132
Number of pages6
JournalSri Lankan Journal of Anaesthesiology
Volume27
Issue number2
DOIs
Publication statusPublished - 01-01-2019
Externally publishedYes

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Bupivacaine
Hemodynamics
Transurethral Resection of Prostate
Muscle Relaxation
Tertiary Healthcare
Chi-Square Distribution
Tertiary Care Centers
Hypotension
India
Anesthesia
Randomized Controlled Trials
ropivacaine

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Kordcal, Abhishek Rao ; Kalyanappagol, Vijaykumar Tipanna ; Rao, Amrut Krishnananda ; Rao, Madhu. / Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries. In: Sri Lankan Journal of Anaesthesiology. 2019 ; Vol. 27, No. 2. pp. 127-132.
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abstract = "Aims: To compare sensory, motor effects and haemodynamic stability of 2ml intrathecal isobaric ropivacaine (0.75{\%}) with 3ml hyperbaric bupivacaine (0.75{\%}) in patients undergoing endoscopic urological surgery. Study Design: Randomized controlled trial involving 142 patients undergoing transurethral resection of prostate (TURP) and URS (urethroscopy) in a tertiary care hospital, India. Methods and materials: Patients were randomly allocated to, Group 1 (3ml of 0.5{\%} (15mg) hyperbaric bupivacaine) and Group 2 (2ml of 0.75{\%} isobaric ropivacaine(15mg)). Onset and highest level of sensory block, onset and duration of motor block, quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied. Statistical analysis used: Unpaired t-test was used to test continuous variables and chi square test/Fisher’s exact test for categorical variables. Results: The mean of highest sensory block, 2 segment regression of sensory block and time for sensory level to regress below T10 was significantly more in group 1 compared to group 2 (P<0.05). There was a significant delay of mean time to onset of motor block to Bromage score 1 in group 2(P<0.001). The mean duration of complete motor blockade was significantly more in group 1 (P value <0.001). Hypotension was most commonly seen in group 1. Conclusion: Ropivacaine provides comparable quality of sensory block but has slower onset and significantly shorter duration of motor block compared to hyperbaric bupivacaine.",
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Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries. / Kordcal, Abhishek Rao; Kalyanappagol, Vijaykumar Tipanna; Rao, Amrut Krishnananda; Rao, Madhu.

In: Sri Lankan Journal of Anaesthesiology, Vol. 27, No. 2, 01.01.2019, p. 127-132.

Research output: Contribution to journalArticle

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AU - Kalyanappagol, Vijaykumar Tipanna

AU - Rao, Amrut Krishnananda

AU - Rao, Madhu

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