Intravenous ribavirin therapy for adenovirus pneumonia

Avinash K. Shetty, Hayley A. Gans, Samuel So, Maria T. Millan, Ann M. Arvin, Kathleen M. Gutierrez

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Abstract

We report on the effectiveness of intravenous ribavirin for severe adenoviral pneumonia in a 10-month-old male following orthotopic liver transplantation. On day 20 post-transplantation, he developed high fever, marked respiratory compromise, and hypoxemia. The chest radiograph showed bilateral pulmonary infiltrates. Samples of bronchoalveolar lavage fluid grew adenovirus, serotype 1. Marked clinical and radiological improvement was noted after intravenous ribavirin therapy. A prospective clinical trial is needed to determine the efficacy of ribavirin therapy for severe adenovirus disease.

Original languageEnglish
Pages (from-to)69-73
Number of pages5
JournalPediatric Pulmonology
Volume29
Issue number1
Publication statusPublished - 01-01-2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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  • Cite this

    Shetty, A. K., Gans, H. A., So, S., Millan, M. T., Arvin, A. M., & Gutierrez, K. M. (2000). Intravenous ribavirin therapy for adenovirus pneumonia. Pediatric Pulmonology, 29(1), 69-73.