Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds

A.M. Krupanidhi, H.M. Vagdevi, C.S. Shreedhara, V.P. Vaidya, K.S. Muralikrishna

Research output: Contribution to journalArticle

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Abstract

Objective: To study the neuropharmacological activities of the ethanolic extract of Dodonaea viscosa seeds. Materials and methods: Neuropharmacological activities includes behavioural assessment, pentobarbitone-induced sleeping time, motor coordination activity and locomotor activity of the Dodonaea viscosa seeds ethanolic extract was evaluated at the dose of 30 mg/kg and 20 mg/ kg (p.o.) respectively. Results: Ethanolic extract of Dodonaea viscosa seeds potentiated phenobarbitone - induced sleeping time, reduced locomotion and the same extract did not induce motor in coordination at dose levels of 30 mg/kg and 20 mg/kg (p.o.). Conclusion: The results of present study have revealed that the ethanolic extract of Dodonaea vsiscosa showed excellent neuropharmacological activities and there is a scope for further envisage.
Original languageEnglish
Pages (from-to)263-268
Number of pages6
JournalJournal of Natural Remedies
Volume7
Issue number2
Publication statusPublished - 2007

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Seeds
Locomotion
Pentobarbital
Phenobarbital
Motor Activity

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Krupanidhi, A. M., Vagdevi, H. M., Shreedhara, C. S., Vaidya, V. P., & Muralikrishna, K. S. (2007). Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds. Journal of Natural Remedies, 7(2), 263-268.
Krupanidhi, A.M. ; Vagdevi, H.M. ; Shreedhara, C.S. ; Vaidya, V.P. ; Muralikrishna, K.S. / Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds. In: Journal of Natural Remedies. 2007 ; Vol. 7, No. 2. pp. 263-268.
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abstract = "Objective: To study the neuropharmacological activities of the ethanolic extract of Dodonaea viscosa seeds. Materials and methods: Neuropharmacological activities includes behavioural assessment, pentobarbitone-induced sleeping time, motor coordination activity and locomotor activity of the Dodonaea viscosa seeds ethanolic extract was evaluated at the dose of 30 mg/kg and 20 mg/ kg (p.o.) respectively. Results: Ethanolic extract of Dodonaea viscosa seeds potentiated phenobarbitone - induced sleeping time, reduced locomotion and the same extract did not induce motor in coordination at dose levels of 30 mg/kg and 20 mg/kg (p.o.). Conclusion: The results of present study have revealed that the ethanolic extract of Dodonaea vsiscosa showed excellent neuropharmacological activities and there is a scope for further envisage.",
author = "A.M. Krupanidhi and H.M. Vagdevi and C.S. Shreedhara and V.P. Vaidya and K.S. Muralikrishna",
note = "Cited By :1 Export Date: 10 November 2017 CODEN: JNROA Correspondence Address: Krupanidhi, A.M.; Bapuji Pharmacy College, Davangere, Karnataka - 577 002, India Chemicals/CAS: alcohol, 64-17-5; amphetamine, 1200-47-1, 139-10-6, 156-34-3, 2706-50-5, 300-62-9, 51-62-7, 60-13-9, 60-15-1; diazepam, 439-14-5; pentobarbital, 57-33-0, 76-74-4 References: Chopra, R.N., Nayar, S.L., Chopra, I.C., (1965) Glossary of Indian Medicinal Plants, I Edn, 100; Kirtikar, K.R., Basu, B.D., Indian Medicinal Plants (2001) Oriental enterprises Dehra Dun, 3, p. 87. , India; Ghisalberti, E.L., (1998) Fitoterapia, 69, p. 99; Pengelly A (1999) Aust. J. Med. Herbalism 1919.11; Chapman, Hall, (1998) Phytochemical Methods, , III Edn, London, Weinhein-New York; 4; Khandelwal KR. (2003) Practical Pharmacognosy, 10th Nirali Prakashan Pune; 149; Reed and Meuch, Turner AR. (1965) Screening methods of Pharmacology. Editor, Academic Press, New York and London; Taber, R.A., Irwin, S., Fox, J.A., Roth, F.E., (1968) Psychopharmacologia, 12, pp. 441-447; Turner, R.A., (1965) Screening methods of Pharmacology, 1, p. 64. , Editor, Academic Press, New York and London; Duham, N.W., Miya, T.S., (1957) J. American Pharm. Assoc, 46, pp. 208-209; Achliya, G.S., Wadodkar, S.G., (2004) J. Ethnopharmacol, 94, pp. 77-83; Achliya, G.S., Wadodkar, S.G., Dorle, A.K., (2004) Indian J. Exp. Biol, 42, pp. 499-503; Martinez, J.L., Oslon, K., Hilstone, C., (1998) Behav. Neuroscience, pp. 487-495; Joyce, E.M., Koob, G.F., Streeker, R., (1981) Brain Res, 221, pp. 359-370; Goodman, Gillmans, (1991) The Basis of Therapeutics, 1, p. 389. , VIII Edn, Pergamon Press New York",
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Krupanidhi, AM, Vagdevi, HM, Shreedhara, CS, Vaidya, VP & Muralikrishna, KS 2007, 'Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds', Journal of Natural Remedies, vol. 7, no. 2, pp. 263-268.

Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds. / Krupanidhi, A.M.; Vagdevi, H.M.; Shreedhara, C.S.; Vaidya, V.P.; Muralikrishna, K.S.

In: Journal of Natural Remedies, Vol. 7, No. 2, 2007, p. 263-268.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds

AU - Krupanidhi, A.M.

AU - Vagdevi, H.M.

AU - Shreedhara, C.S.

AU - Vaidya, V.P.

AU - Muralikrishna, K.S.

N1 - Cited By :1 Export Date: 10 November 2017 CODEN: JNROA Correspondence Address: Krupanidhi, A.M.; Bapuji Pharmacy College, Davangere, Karnataka - 577 002, India Chemicals/CAS: alcohol, 64-17-5; amphetamine, 1200-47-1, 139-10-6, 156-34-3, 2706-50-5, 300-62-9, 51-62-7, 60-13-9, 60-15-1; diazepam, 439-14-5; pentobarbital, 57-33-0, 76-74-4 References: Chopra, R.N., Nayar, S.L., Chopra, I.C., (1965) Glossary of Indian Medicinal Plants, I Edn, 100; Kirtikar, K.R., Basu, B.D., Indian Medicinal Plants (2001) Oriental enterprises Dehra Dun, 3, p. 87. , India; Ghisalberti, E.L., (1998) Fitoterapia, 69, p. 99; Pengelly A (1999) Aust. J. Med. Herbalism 1919.11; Chapman, Hall, (1998) Phytochemical Methods, , III Edn, London, Weinhein-New York; 4; Khandelwal KR. (2003) Practical Pharmacognosy, 10th Nirali Prakashan Pune; 149; Reed and Meuch, Turner AR. (1965) Screening methods of Pharmacology. Editor, Academic Press, New York and London; Taber, R.A., Irwin, S., Fox, J.A., Roth, F.E., (1968) Psychopharmacologia, 12, pp. 441-447; Turner, R.A., (1965) Screening methods of Pharmacology, 1, p. 64. , Editor, Academic Press, New York and London; Duham, N.W., Miya, T.S., (1957) J. American Pharm. Assoc, 46, pp. 208-209; Achliya, G.S., Wadodkar, S.G., (2004) J. Ethnopharmacol, 94, pp. 77-83; Achliya, G.S., Wadodkar, S.G., Dorle, A.K., (2004) Indian J. Exp. Biol, 42, pp. 499-503; Martinez, J.L., Oslon, K., Hilstone, C., (1998) Behav. Neuroscience, pp. 487-495; Joyce, E.M., Koob, G.F., Streeker, R., (1981) Brain Res, 221, pp. 359-370; Goodman, Gillmans, (1991) The Basis of Therapeutics, 1, p. 389. , VIII Edn, Pergamon Press New York

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N2 - Objective: To study the neuropharmacological activities of the ethanolic extract of Dodonaea viscosa seeds. Materials and methods: Neuropharmacological activities includes behavioural assessment, pentobarbitone-induced sleeping time, motor coordination activity and locomotor activity of the Dodonaea viscosa seeds ethanolic extract was evaluated at the dose of 30 mg/kg and 20 mg/ kg (p.o.) respectively. Results: Ethanolic extract of Dodonaea viscosa seeds potentiated phenobarbitone - induced sleeping time, reduced locomotion and the same extract did not induce motor in coordination at dose levels of 30 mg/kg and 20 mg/kg (p.o.). Conclusion: The results of present study have revealed that the ethanolic extract of Dodonaea vsiscosa showed excellent neuropharmacological activities and there is a scope for further envisage.

AB - Objective: To study the neuropharmacological activities of the ethanolic extract of Dodonaea viscosa seeds. Materials and methods: Neuropharmacological activities includes behavioural assessment, pentobarbitone-induced sleeping time, motor coordination activity and locomotor activity of the Dodonaea viscosa seeds ethanolic extract was evaluated at the dose of 30 mg/kg and 20 mg/ kg (p.o.) respectively. Results: Ethanolic extract of Dodonaea viscosa seeds potentiated phenobarbitone - induced sleeping time, reduced locomotion and the same extract did not induce motor in coordination at dose levels of 30 mg/kg and 20 mg/kg (p.o.). Conclusion: The results of present study have revealed that the ethanolic extract of Dodonaea vsiscosa showed excellent neuropharmacological activities and there is a scope for further envisage.

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JO - Journal of Natural Remedies

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Krupanidhi AM, Vagdevi HM, Shreedhara CS, Vaidya VP, Muralikrishna KS. Investigation of neuropharmacological activities of ethanolic extract of Dodonaea viscosa seeds. Journal of Natural Remedies. 2007;7(2):263-268.