Isolated third nerve palsy

A rare neurological presentation of Burkitt's lymphoma

Siddhesh Arun Kalantri, Akshatha Nayak, Saikat Datta, Maitreyee Bhattacharyya

    Research output: Contribution to journalArticle

    Abstract

    Lymphoma patient presenting with isolated third nerve palsy is relatively rare, and diagnosis of underlying disease may be challenging. Until this date, less than 20 cases have been described in the literature. This is the case of a 3-year-old boy who presented to neurologist with ptosis of left eye for 8 days. On examination, abdominal mass was detected, and the child was referred to paediatric surgery department. Laparotomy and excision of the mass was done. Histopathology and immunohistochemistry of the mass confirmed it to be a case of Burkitt's lymphoma. At this point, the patient was referred to haematology department. Contrast-enhanced CT brain showed infiltration around left cavernous sinus. Patient was treated with two cycles of R-CODOX-M/R-IVAC. Ptosis improved completely within few days of starting chemotherapy. Follow-up positron emission tomography CT scan done after the second cycle of chemotherapy revealed no metabolically active disease.

    Original languageEnglish
    Article number225
    JournalBMJ Case Reports
    Volume2017
    DOIs
    Publication statusPublished - 01-01-2017

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    Oculomotor Nerve Diseases
    Burkitt Lymphoma
    Drug Therapy
    Cavernous Sinus
    Hematology
    Positron-Emission Tomography
    Laparotomy
    Lymphoma
    Immunohistochemistry
    Pediatrics
    Brain

    All Science Journal Classification (ASJC) codes

    • Medicine(all)

    Cite this

    Kalantri, Siddhesh Arun ; Nayak, Akshatha ; Datta, Saikat ; Bhattacharyya, Maitreyee. / Isolated third nerve palsy : A rare neurological presentation of Burkitt's lymphoma. In: BMJ Case Reports. 2017 ; Vol. 2017.
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    abstract = "Lymphoma patient presenting with isolated third nerve palsy is relatively rare, and diagnosis of underlying disease may be challenging. Until this date, less than 20 cases have been described in the literature. This is the case of a 3-year-old boy who presented to neurologist with ptosis of left eye for 8 days. On examination, abdominal mass was detected, and the child was referred to paediatric surgery department. Laparotomy and excision of the mass was done. Histopathology and immunohistochemistry of the mass confirmed it to be a case of Burkitt's lymphoma. At this point, the patient was referred to haematology department. Contrast-enhanced CT brain showed infiltration around left cavernous sinus. Patient was treated with two cycles of R-CODOX-M/R-IVAC. Ptosis improved completely within few days of starting chemotherapy. Follow-up positron emission tomography CT scan done after the second cycle of chemotherapy revealed no metabolically active disease.",
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    Isolated third nerve palsy : A rare neurological presentation of Burkitt's lymphoma. / Kalantri, Siddhesh Arun; Nayak, Akshatha; Datta, Saikat; Bhattacharyya, Maitreyee.

    In: BMJ Case Reports, Vol. 2017, 225, 01.01.2017.

    Research output: Contribution to journalArticle

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    T2 - A rare neurological presentation of Burkitt's lymphoma

    AU - Kalantri, Siddhesh Arun

    AU - Nayak, Akshatha

    AU - Datta, Saikat

    AU - Bhattacharyya, Maitreyee

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    AB - Lymphoma patient presenting with isolated third nerve palsy is relatively rare, and diagnosis of underlying disease may be challenging. Until this date, less than 20 cases have been described in the literature. This is the case of a 3-year-old boy who presented to neurologist with ptosis of left eye for 8 days. On examination, abdominal mass was detected, and the child was referred to paediatric surgery department. Laparotomy and excision of the mass was done. Histopathology and immunohistochemistry of the mass confirmed it to be a case of Burkitt's lymphoma. At this point, the patient was referred to haematology department. Contrast-enhanced CT brain showed infiltration around left cavernous sinus. Patient was treated with two cycles of R-CODOX-M/R-IVAC. Ptosis improved completely within few days of starting chemotherapy. Follow-up positron emission tomography CT scan done after the second cycle of chemotherapy revealed no metabolically active disease.

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