Lactate dehydrogenase estimation in follicular fluid: Correlation with patient age, follicle size and super ovulation in ART cycles

Satish Kumar Adiga, Pratap Kumar, Shivananda Nayak Bijoor

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To quantify the lactate dehydrogenase (LDH) level in human follicular fluids, and to define its relationship with follicle size, patient age, serum estradiol (E2) level, and the amount of gonadotropins administered during superovulation in ART cycles. Study design: In this prospective study, 21 women undergoing ART treatment were selected. Follicular fluid from the largest follicle of both ovaries was collected from each patient on the day of oocyte aspiration and analyzed for LDH. Serum oestradiol was estimated on the day of hCG administration. Relationship between LDH level and (1) patient age, (2) follicle size, (3) follicle stimulating hormone administered during superovulation period and (4) serum oestradiol was studied. Result(s): LDH activity increased with chronological age of the patient. As follicular size (diameter) increased, increase in the LDH concentration in follicular fluid was observed. Serum estradiol level did not show any relationship with LDH activity. Similarly, administration of various doses of follicle stimulating hormone during superovulation did not show any correlation with LDH level. Conclusion(s): Follicular fluid LDH level has shown association with patient age and the follicle size, however, no significant association was found with other parameters studied.

Original languageEnglish
Pages (from-to)150-154
Number of pages5
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Volume105
Issue number2
DOIs
Publication statusPublished - 15-11-2002

Fingerprint

Follicular Fluid
Ovulation
L-Lactate Dehydrogenase
Superovulation
Estradiol
Follicle Stimulating Hormone
Serum
Oocyte Retrieval
Gonadotropins
Ovary
Prospective Studies

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

@article{93358bf51acb41e19bf19d6edbb20604,
title = "Lactate dehydrogenase estimation in follicular fluid: Correlation with patient age, follicle size and super ovulation in ART cycles",
abstract = "Objective: To quantify the lactate dehydrogenase (LDH) level in human follicular fluids, and to define its relationship with follicle size, patient age, serum estradiol (E2) level, and the amount of gonadotropins administered during superovulation in ART cycles. Study design: In this prospective study, 21 women undergoing ART treatment were selected. Follicular fluid from the largest follicle of both ovaries was collected from each patient on the day of oocyte aspiration and analyzed for LDH. Serum oestradiol was estimated on the day of hCG administration. Relationship between LDH level and (1) patient age, (2) follicle size, (3) follicle stimulating hormone administered during superovulation period and (4) serum oestradiol was studied. Result(s): LDH activity increased with chronological age of the patient. As follicular size (diameter) increased, increase in the LDH concentration in follicular fluid was observed. Serum estradiol level did not show any relationship with LDH activity. Similarly, administration of various doses of follicle stimulating hormone during superovulation did not show any correlation with LDH level. Conclusion(s): Follicular fluid LDH level has shown association with patient age and the follicle size, however, no significant association was found with other parameters studied.",
author = "Adiga, {Satish Kumar} and Pratap Kumar and Bijoor, {Shivananda Nayak}",
year = "2002",
month = "11",
day = "15",
doi = "10.1016/S0301-2115(02)00193-8",
language = "English",
volume = "105",
pages = "150--154",
journal = "European Journal of Obstetrics and Gynecology and Reproductive Biology",
issn = "0028-2243",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Lactate dehydrogenase estimation in follicular fluid

T2 - Correlation with patient age, follicle size and super ovulation in ART cycles

AU - Adiga, Satish Kumar

AU - Kumar, Pratap

AU - Bijoor, Shivananda Nayak

PY - 2002/11/15

Y1 - 2002/11/15

N2 - Objective: To quantify the lactate dehydrogenase (LDH) level in human follicular fluids, and to define its relationship with follicle size, patient age, serum estradiol (E2) level, and the amount of gonadotropins administered during superovulation in ART cycles. Study design: In this prospective study, 21 women undergoing ART treatment were selected. Follicular fluid from the largest follicle of both ovaries was collected from each patient on the day of oocyte aspiration and analyzed for LDH. Serum oestradiol was estimated on the day of hCG administration. Relationship between LDH level and (1) patient age, (2) follicle size, (3) follicle stimulating hormone administered during superovulation period and (4) serum oestradiol was studied. Result(s): LDH activity increased with chronological age of the patient. As follicular size (diameter) increased, increase in the LDH concentration in follicular fluid was observed. Serum estradiol level did not show any relationship with LDH activity. Similarly, administration of various doses of follicle stimulating hormone during superovulation did not show any correlation with LDH level. Conclusion(s): Follicular fluid LDH level has shown association with patient age and the follicle size, however, no significant association was found with other parameters studied.

AB - Objective: To quantify the lactate dehydrogenase (LDH) level in human follicular fluids, and to define its relationship with follicle size, patient age, serum estradiol (E2) level, and the amount of gonadotropins administered during superovulation in ART cycles. Study design: In this prospective study, 21 women undergoing ART treatment were selected. Follicular fluid from the largest follicle of both ovaries was collected from each patient on the day of oocyte aspiration and analyzed for LDH. Serum oestradiol was estimated on the day of hCG administration. Relationship between LDH level and (1) patient age, (2) follicle size, (3) follicle stimulating hormone administered during superovulation period and (4) serum oestradiol was studied. Result(s): LDH activity increased with chronological age of the patient. As follicular size (diameter) increased, increase in the LDH concentration in follicular fluid was observed. Serum estradiol level did not show any relationship with LDH activity. Similarly, administration of various doses of follicle stimulating hormone during superovulation did not show any correlation with LDH level. Conclusion(s): Follicular fluid LDH level has shown association with patient age and the follicle size, however, no significant association was found with other parameters studied.

UR - http://www.scopus.com/inward/record.url?scp=0037110883&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037110883&partnerID=8YFLogxK

U2 - 10.1016/S0301-2115(02)00193-8

DO - 10.1016/S0301-2115(02)00193-8

M3 - Article

C2 - 12381478

AN - SCOPUS:0037110883

VL - 105

SP - 150

EP - 154

JO - European Journal of Obstetrics and Gynecology and Reproductive Biology

JF - European Journal of Obstetrics and Gynecology and Reproductive Biology

SN - 0028-2243

IS - 2

ER -