Langerhans cell histiocytosis of mediastinal node

Urmila N. Khadilkar, A. T.K. Rao, Kausalya Kumari Sahoo, Mukta R. Pai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.

Original languageEnglish
Pages (from-to)294-296
Number of pages3
JournalIndian Journal of Pediatrics
Volume75
Issue number3
DOIs
Publication statusPublished - 01-03-2008

Fingerprint

Langerhans Cell Histiocytosis
S100 Proteins
Bone Diseases
Fine Needle Biopsy
Cell Biology
Lymph Nodes
Immunohistochemistry
Biopsy

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Khadilkar, Urmila N. ; Rao, A. T.K. ; Sahoo, Kausalya Kumari ; Pai, Mukta R. / Langerhans cell histiocytosis of mediastinal node. In: Indian Journal of Pediatrics. 2008 ; Vol. 75, No. 3. pp. 294-296.
@article{54d619de40f149219c5dec810e4eb11f,
title = "Langerhans cell histiocytosis of mediastinal node",
abstract = "The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.",
author = "Khadilkar, {Urmila N.} and Rao, {A. T.K.} and Sahoo, {Kausalya Kumari} and Pai, {Mukta R.}",
year = "2008",
month = "3",
day = "1",
doi = "10.1007/s12098-008-0064-z",
language = "English",
volume = "75",
pages = "294--296",
journal = "Indian Journal of Practical Pediatrics",
issn = "0972-9607",
publisher = "Springer India",
number = "3",

}

Langerhans cell histiocytosis of mediastinal node. / Khadilkar, Urmila N.; Rao, A. T.K.; Sahoo, Kausalya Kumari; Pai, Mukta R.

In: Indian Journal of Pediatrics, Vol. 75, No. 3, 01.03.2008, p. 294-296.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Langerhans cell histiocytosis of mediastinal node

AU - Khadilkar, Urmila N.

AU - Rao, A. T.K.

AU - Sahoo, Kausalya Kumari

AU - Pai, Mukta R.

PY - 2008/3/1

Y1 - 2008/3/1

N2 - The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.

AB - The predominant clinical and radiological features of Langerhans Cell Histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation. In the present study, LCH was presumptively diagnosed on Ultrasound guided Fine needle aspiration cytology (FNAC) of the mediastinal lymph node in a 18 month-old child. The diagnosis was confirmed by histological examination of the biopsy material. S-100 protein localization in the LCH cells is often positive on immunohistochemistry.

UR - http://www.scopus.com/inward/record.url?scp=44049094308&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44049094308&partnerID=8YFLogxK

U2 - 10.1007/s12098-008-0064-z

DO - 10.1007/s12098-008-0064-z

M3 - Article

C2 - 18376103

AN - SCOPUS:44049094308

VL - 75

SP - 294

EP - 296

JO - Indian Journal of Practical Pediatrics

JF - Indian Journal of Practical Pediatrics

SN - 0972-9607

IS - 3

ER -