TY - JOUR
T1 - Leptospirosis in Coastal South India
T2 - A Facility Based Study
AU - Holla, Ramesh
AU - Darshan, Bhagwan
AU - Pandey, Latika
AU - Unnikrishnan, Bhaskaran
AU - Kumar, Nithin
AU - Thapar, Rekha
AU - Mithra, Prasanna
AU - Kulkarni, Vaman
N1 - Funding Information:
The authors wish to acknowledge the support provided by the Department of Community Medicine, Kasturba Medical College, Mangalore, and Manipal Academy of Higher Education for encouraging research and its publication in international journals of repute.
Publisher Copyright:
© 2018 Ramesh Holla et al.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.
AB - Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.
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U2 - 10.1155/2018/1759125
DO - 10.1155/2018/1759125
M3 - Article
C2 - 29862254
AN - SCOPUS:85047846808
SN - 2314-6133
VL - 2018
JO - BioMed Research International
JF - BioMed Research International
M1 - 1759125
ER -
