Leptospirosis in Coastal South India: A Facility Based Study

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Abstract

Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.

Original languageEnglish
Article number1759125
JournalBioMed Research International
Volume2018
DOIs
Publication statusPublished - 01-01-2018

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Leptospirosis
Public health
Medical problems
Developing countries
India
Data acquisition
Endemic Diseases
Asymptomatic Infections
Acute Kidney Injury
Developing Countries
Registries
Fever
Retrospective Studies
Public Health
Demography
Mortality
Population

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

@article{6d2ae933a52f47c88c6a31a0939b066a,
title = "Leptospirosis in Coastal South India: A Facility Based Study",
abstract = "Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1{\%}) at the time of admission. Acute renal failure was found to be the most common complication (79.2{\%}). Case fatality rate was found to be 3.5{\%}. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.",
author = "Ramesh Holla and Bhagwan Darshan and Latika Pandey and Bhaskaran Unnikrishnan and Nithin Kumar and Rekha Thapar and Prasanna Mithra and Vaman Kulkarni",
year = "2018",
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doi = "10.1155/2018/1759125",
language = "English",
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journal = "BioMed Research International",
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T1 - Leptospirosis in Coastal South India

T2 - A Facility Based Study

AU - Holla, Ramesh

AU - Darshan, Bhagwan

AU - Pandey, Latika

AU - Unnikrishnan, Bhaskaran

AU - Kumar, Nithin

AU - Thapar, Rekha

AU - Mithra, Prasanna

AU - Kulkarni, Vaman

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.

AB - Background. Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective. The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods. This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results. The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion. High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.

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