Abstract
Purpose: The study evaluated 2 biomarkers (myeloperoxidase [MPO] and alkaline phosphatase) along with clinical parameters in periimplant sulcus fluid (PISF) in conditions of periimplant health and disease. The effect of nonsurgical therapy was also evaluated on the biochemical and clinical parameters in diseased implants at 3 months after the baseline. Materials and Methods: A total number of 30 implants were studied in 20 subjects and divided into healthy group (group 1) and periimplant disease group (group 2). PISF was collected in both groups along with recording of clinical parameters. The periimplant disease group was then instituted a nonsurgical anti-infective therapy. The clinical and biochemical parameters were evaluated and compared at baseline and at the end of 3 months. Results: Group 2 showed statistically significant higher PISF MPO values at baseline as compared with groups 1 and 2 (at 3 months) (P < 0.001). Also, difference in the mean value of PISF MPO in group 2 (at 3 months) was greater than that in group 1 and was statistically nonsignificant (P 1.85). Conclusion: Within confines of the study, it can be concluded that evaluation of biochemical markers in PISF can be a useful diagnostic tool to aid the clinician in decision making regarding the management of the condition. ©
| Original language | English |
|---|---|
| Pages (from-to) | 434-440 |
| Number of pages | 7 |
| Journal | Implant Dentistry |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 01-01-2015 |
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All Science Journal Classification (ASJC) codes
- Oral Surgery
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Levels of Myeloperoxidase and Alkaline Phosphatase in Periimplant Sulcus Fluid in Health and Disease and after Nonsurgical Therapy. / Malik, Nikita; Naik, Dilip; Uppoor, Ashita.
In: Implant Dentistry, Vol. 24, No. 4, 01.01.2015, p. 434-440.Research output: Contribution to journal › Article
TY - JOUR
T1 - Levels of Myeloperoxidase and Alkaline Phosphatase in Periimplant Sulcus Fluid in Health and Disease and after Nonsurgical Therapy
AU - Malik, Nikita
AU - Naik, Dilip
AU - Uppoor, Ashita
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Purpose: The study evaluated 2 biomarkers (myeloperoxidase [MPO] and alkaline phosphatase) along with clinical parameters in periimplant sulcus fluid (PISF) in conditions of periimplant health and disease. The effect of nonsurgical therapy was also evaluated on the biochemical and clinical parameters in diseased implants at 3 months after the baseline. Materials and Methods: A total number of 30 implants were studied in 20 subjects and divided into healthy group (group 1) and periimplant disease group (group 2). PISF was collected in both groups along with recording of clinical parameters. The periimplant disease group was then instituted a nonsurgical anti-infective therapy. The clinical and biochemical parameters were evaluated and compared at baseline and at the end of 3 months. Results: Group 2 showed statistically significant higher PISF MPO values at baseline as compared with groups 1 and 2 (at 3 months) (P < 0.001). Also, difference in the mean value of PISF MPO in group 2 (at 3 months) was greater than that in group 1 and was statistically nonsignificant (P 1.85). Conclusion: Within confines of the study, it can be concluded that evaluation of biochemical markers in PISF can be a useful diagnostic tool to aid the clinician in decision making regarding the management of the condition. ©
AB - Purpose: The study evaluated 2 biomarkers (myeloperoxidase [MPO] and alkaline phosphatase) along with clinical parameters in periimplant sulcus fluid (PISF) in conditions of periimplant health and disease. The effect of nonsurgical therapy was also evaluated on the biochemical and clinical parameters in diseased implants at 3 months after the baseline. Materials and Methods: A total number of 30 implants were studied in 20 subjects and divided into healthy group (group 1) and periimplant disease group (group 2). PISF was collected in both groups along with recording of clinical parameters. The periimplant disease group was then instituted a nonsurgical anti-infective therapy. The clinical and biochemical parameters were evaluated and compared at baseline and at the end of 3 months. Results: Group 2 showed statistically significant higher PISF MPO values at baseline as compared with groups 1 and 2 (at 3 months) (P < 0.001). Also, difference in the mean value of PISF MPO in group 2 (at 3 months) was greater than that in group 1 and was statistically nonsignificant (P 1.85). Conclusion: Within confines of the study, it can be concluded that evaluation of biochemical markers in PISF can be a useful diagnostic tool to aid the clinician in decision making regarding the management of the condition. ©
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U2 - 10.1097/ID.0000000000000277
DO - 10.1097/ID.0000000000000277
M3 - Article
VL - 24
SP - 434
EP - 440
JO - Implant Dentistry
JF - Implant Dentistry
SN - 1056-6163
IS - 4
ER -