Abstract
Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.
| Original language | English |
|---|---|
| Pages (from-to) | 2558-2568 |
| Number of pages | 11 |
| Journal | Journal of the American Ceramic Society |
| Volume | 102 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 01-05-2019 |
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All Science Journal Classification (ASJC) codes
- Ceramics and Composites
- Materials Chemistry
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Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. / Karthi, Sekar; Govindan, Raji; Gangadharan, Ajithkumar; Dannangoda, Gamage Chamath; Martirosyan, Karen S.; Sardar, Dhiraj K.; Chidangil, Santhosh; Girija, Easwaradas Kreedapathy.
In: Journal of the American Ceramic Society, Vol. 102, No. 5, 01.05.2019, p. 2558-2568.Research output: Contribution to journal › Article
TY - JOUR
T1 - Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications
AU - Karthi, Sekar
AU - Govindan, Raji
AU - Gangadharan, Ajithkumar
AU - Dannangoda, Gamage Chamath
AU - Martirosyan, Karen S.
AU - Sardar, Dhiraj K.
AU - Chidangil, Santhosh
AU - Girija, Easwaradas Kreedapathy
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.
AB - Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.
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U2 - 10.1111/jace.16090
DO - 10.1111/jace.16090
M3 - Article
VL - 102
SP - 2558
EP - 2568
JO - Journal of the American Ceramic Society
JF - Journal of the American Ceramic Society
SN - 0002-7820
IS - 5
ER -