Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications

Sekar Karthi, Raji Govindan, Ajithkumar Gangadharan, Gamage Chamath Dannangoda, Karen S. Martirosyan, Dhiraj K. Sardar, Santhosh Chidangil, Easwaradas Kreedapathy Girija

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Abstract

Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.

Original languageEnglish
Pages (from-to)2558-2568
Number of pages11
JournalJournal of the American Ceramic Society
Volume102
Issue number5
DOIs
Publication statusPublished - 01-05-2019

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All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Materials Chemistry

Cite this

Karthi, S., Govindan, R., Gangadharan, A., Dannangoda, G. C., Martirosyan, K. S., Sardar, D. K., ... Girija, E. K. (2019). Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. Journal of the American Ceramic Society, 102(5), 2558-2568. https://doi.org/10.1111/jace.16090