Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications

Sekar Karthi, Raji Govindan, Ajithkumar Gangadharan, Gamage Chamath Dannangoda, Karen S. Martirosyan, Dhiraj K. Sardar, Santhosh Chidangil, Easwaradas Kreedapathy Girija

Research output: Contribution to journalArticle

Abstract

Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.

Original languageEnglish
Pages (from-to)2558-2568
Number of pages11
JournalJournal of the American Ceramic Society
Volume102
Issue number5
DOIs
Publication statusPublished - 01-05-2019

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Nanostructures
Nanoparticles
Magnetic variables measurement
Saturation magnetization
X ray diffraction analysis
fluorapatite
Electron microscopes
Cells
Infrared radiation
Temperature

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Materials Chemistry

Cite this

Karthi, S., Govindan, R., Gangadharan, A., Dannangoda, G. C., Martirosyan, K. S., Sardar, D. K., ... Girija, E. K. (2019). Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. Journal of the American Ceramic Society, 102(5), 2558-2568. https://doi.org/10.1111/jace.16090
Karthi, Sekar ; Govindan, Raji ; Gangadharan, Ajithkumar ; Dannangoda, Gamage Chamath ; Martirosyan, Karen S. ; Sardar, Dhiraj K. ; Chidangil, Santhosh ; Girija, Easwaradas Kreedapathy. / Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. In: Journal of the American Ceramic Society. 2019 ; Vol. 102, No. 5. pp. 2558-2568.
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Karthi, S, Govindan, R, Gangadharan, A, Dannangoda, GC, Martirosyan, KS, Sardar, DK, Chidangil, S & Girija, EK 2019, 'Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications' Journal of the American Ceramic Society, vol. 102, no. 5, pp. 2558-2568. https://doi.org/10.1111/jace.16090

Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. / Karthi, Sekar; Govindan, Raji; Gangadharan, Ajithkumar; Dannangoda, Gamage Chamath; Martirosyan, Karen S.; Sardar, Dhiraj K.; Chidangil, Santhosh; Girija, Easwaradas Kreedapathy.

In: Journal of the American Ceramic Society, Vol. 102, No. 5, 01.05.2019, p. 2558-2568.

Research output: Contribution to journalArticle

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AU - Govindan, Raji

AU - Gangadharan, Ajithkumar

AU - Dannangoda, Gamage Chamath

AU - Martirosyan, Karen S.

AU - Sardar, Dhiraj K.

AU - Chidangil, Santhosh

AU - Girija, Easwaradas Kreedapathy

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AB - Luminomagnetic nanostructured Nd 3+ doped fluorapatite (FAP) coated Fe 3 O 4 nanoparticles were produced by hydrothermal method. X-ray diffraction analysis indicates that the prepared nanoparticles contain both FAP and Fe 3 O 4 phases. Electron microscope analysis shows the formation of nanoparticles of Fe 3 O 4 encased in rod shaped FAP nanoparticles of average length 40 nm. Magnetic measurements confirm the room temperature superparamagnetic nature of the nanoparticles with saturation magnetization value up to 7.8 emu/g. The prepared nanoparticles display strong near infrared (NIR) emission at 1060 nm under 800 nm excitation. Cell viability studies for 72 hour demonstrate the survival rate of over 84% with 500 μg/mL concentration indicating the good cytocompatibility of the prepared materials. The present Nd 3+ doped FAP coated Fe 3 O 4 nanostructure provides an excellent multifunctional platform for diagnostics and therapeutic applications.

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Karthi S, Govindan R, Gangadharan A, Dannangoda GC, Martirosyan KS, Sardar DK et al. Luminomagnetic Nd 3+ doped fluorapatite coated Fe 3 O 4 nanostructures for biomedical applications. Journal of the American Ceramic Society. 2019 May 1;102(5):2558-2568. https://doi.org/10.1111/jace.16090