Lymphocytic variant of hypereosinophilic syndrome complicated by myocarditis

Sravan Kumar, Jagadesh Madireddi, Chandhra Shekar Udyavara Kudru, Shiva Shankar

Research output: Contribution to journalArticle

Abstract

A 26 year-old-male with nil significant past medical history presented to us with swelling of left lower limb since 2 weeks. He has tachyapnea and tachycardia. His JVP was normal and cardiac auscultation was normal. Examination was suggestive of deep vein thrombosis (DVT) of the left lower limb. Doppler of lower limb confirmed this and patient was appropriately placed on anti-coagulation. He had persistently elevated blood eosinophil counts. Bone marrow biopsy was and mutational analysis confirmed presence of lymphocytic variant of hypereosinophilic syndrome (HES). He continued to have tachycardia and cardiac enzymes were positive. Electrocardiogram revealed sinus tachycardia and echo was normal. After ruling out the possibility of pulmonary thromboembolism with CT pulmonary angiogram, myocarditis was attributed to HES. He was promptly treated glucocorticoids which were later tapered gradually in lieu of improvement of his clinical condition and declining eosinophil counts. He was discharged and was under regular follow-up.

Original languageEnglish
Pages (from-to)184-186
Number of pages3
JournalJournal of Cardiovascular Disease Research
Volume6
Issue number4
DOIs
Publication statusPublished - 01-10-2015

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Hypereosinophilic Syndrome
Myocarditis
Lower Extremity
Eosinophils
Tachycardia
Heart Auscultation
Sinus Tachycardia
Pulmonary Embolism
Venous Thrombosis
Glucocorticoids
Angiography
Electrocardiography
Bone Marrow
Biopsy
Lung
Enzymes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

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abstract = "A 26 year-old-male with nil significant past medical history presented to us with swelling of left lower limb since 2 weeks. He has tachyapnea and tachycardia. His JVP was normal and cardiac auscultation was normal. Examination was suggestive of deep vein thrombosis (DVT) of the left lower limb. Doppler of lower limb confirmed this and patient was appropriately placed on anti-coagulation. He had persistently elevated blood eosinophil counts. Bone marrow biopsy was and mutational analysis confirmed presence of lymphocytic variant of hypereosinophilic syndrome (HES). He continued to have tachycardia and cardiac enzymes were positive. Electrocardiogram revealed sinus tachycardia and echo was normal. After ruling out the possibility of pulmonary thromboembolism with CT pulmonary angiogram, myocarditis was attributed to HES. He was promptly treated glucocorticoids which were later tapered gradually in lieu of improvement of his clinical condition and declining eosinophil counts. He was discharged and was under regular follow-up.",
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Lymphocytic variant of hypereosinophilic syndrome complicated by myocarditis. / Kumar, Sravan; Madireddi, Jagadesh; Kudru, Chandhra Shekar Udyavara; Shankar, Shiva.

In: Journal of Cardiovascular Disease Research, Vol. 6, No. 4, 01.10.2015, p. 184-186.

Research output: Contribution to journalArticle

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AU - Kumar, Sravan

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