Mandibular Canal Widening and Bell's Palsy

Sequelae of Perineural Invasion in Oral Cancer

Gopinath Thilak Parepady Sundar, Vishwanath Sherigar, Sameep S. Shetty, Shree Satya, Sourabh M. Gohil

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Perineural invasion is an underrecognized route of metastatic spread along the nerve bundles within the nerve sheath into the surrounding tissues. It hinders the ability to establish local control as tumour cells can traverse along nerve tracts well beyond the extent of any local invasion rendering them inoperable and unresectable. Perineural invasion is a marker of poor prognosis. Oral submucous fibrosis with oral cancer constitutes a clinicopathologically distinct disease. Our case highlights an enigmatic presentation of oral submucous fibrosis and its coexistence with oral cancer presenting with unusual neurological disturbance of the inferior alveolar nerve and facial nerve and diffuse widening of the mandibular canal. The objective of this case report is to enumerate the significance of perineural invasion in determining the course of the disease and necessitate the need for future studies that can shed light on molecular mediators and pathogenesis of perineural spread.

Original languageEnglish
Article number3010934
JournalCase Reports in Dentistry
Volume2016
DOIs
Publication statusPublished - 01-01-2016

Fingerprint

Oral Submucous Fibrosis
Bell Palsy
Mouth Neoplasms
Mandibular Nerve
Facial Nerve
Neoplasms

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Sundar, G. T. P., Sherigar, V., Shetty, S. S., Satya, S., & Gohil, S. M. (2016). Mandibular Canal Widening and Bell's Palsy: Sequelae of Perineural Invasion in Oral Cancer. Case Reports in Dentistry, 2016, [3010934]. https://doi.org/10.1155/2016/3010934
Sundar, Gopinath Thilak Parepady ; Sherigar, Vishwanath ; Shetty, Sameep S. ; Satya, Shree ; Gohil, Sourabh M. / Mandibular Canal Widening and Bell's Palsy : Sequelae of Perineural Invasion in Oral Cancer. In: Case Reports in Dentistry. 2016 ; Vol. 2016.
@article{618581854faf450db1ee4fd3b35cf914,
title = "Mandibular Canal Widening and Bell's Palsy: Sequelae of Perineural Invasion in Oral Cancer",
abstract = "Perineural invasion is an underrecognized route of metastatic spread along the nerve bundles within the nerve sheath into the surrounding tissues. It hinders the ability to establish local control as tumour cells can traverse along nerve tracts well beyond the extent of any local invasion rendering them inoperable and unresectable. Perineural invasion is a marker of poor prognosis. Oral submucous fibrosis with oral cancer constitutes a clinicopathologically distinct disease. Our case highlights an enigmatic presentation of oral submucous fibrosis and its coexistence with oral cancer presenting with unusual neurological disturbance of the inferior alveolar nerve and facial nerve and diffuse widening of the mandibular canal. The objective of this case report is to enumerate the significance of perineural invasion in determining the course of the disease and necessitate the need for future studies that can shed light on molecular mediators and pathogenesis of perineural spread.",
author = "Sundar, {Gopinath Thilak Parepady} and Vishwanath Sherigar and Shetty, {Sameep S.} and Shree Satya and Gohil, {Sourabh M.}",
year = "2016",
month = "1",
day = "1",
doi = "10.1155/2016/3010934",
language = "English",
volume = "2016",
journal = "Case Reports in Dentistry",
issn = "2090-6447",
publisher = "Hindawi Publishing Corporation",

}

Mandibular Canal Widening and Bell's Palsy : Sequelae of Perineural Invasion in Oral Cancer. / Sundar, Gopinath Thilak Parepady; Sherigar, Vishwanath; Shetty, Sameep S.; Satya, Shree; Gohil, Sourabh M.

In: Case Reports in Dentistry, Vol. 2016, 3010934, 01.01.2016.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Mandibular Canal Widening and Bell's Palsy

T2 - Sequelae of Perineural Invasion in Oral Cancer

AU - Sundar, Gopinath Thilak Parepady

AU - Sherigar, Vishwanath

AU - Shetty, Sameep S.

AU - Satya, Shree

AU - Gohil, Sourabh M.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Perineural invasion is an underrecognized route of metastatic spread along the nerve bundles within the nerve sheath into the surrounding tissues. It hinders the ability to establish local control as tumour cells can traverse along nerve tracts well beyond the extent of any local invasion rendering them inoperable and unresectable. Perineural invasion is a marker of poor prognosis. Oral submucous fibrosis with oral cancer constitutes a clinicopathologically distinct disease. Our case highlights an enigmatic presentation of oral submucous fibrosis and its coexistence with oral cancer presenting with unusual neurological disturbance of the inferior alveolar nerve and facial nerve and diffuse widening of the mandibular canal. The objective of this case report is to enumerate the significance of perineural invasion in determining the course of the disease and necessitate the need for future studies that can shed light on molecular mediators and pathogenesis of perineural spread.

AB - Perineural invasion is an underrecognized route of metastatic spread along the nerve bundles within the nerve sheath into the surrounding tissues. It hinders the ability to establish local control as tumour cells can traverse along nerve tracts well beyond the extent of any local invasion rendering them inoperable and unresectable. Perineural invasion is a marker of poor prognosis. Oral submucous fibrosis with oral cancer constitutes a clinicopathologically distinct disease. Our case highlights an enigmatic presentation of oral submucous fibrosis and its coexistence with oral cancer presenting with unusual neurological disturbance of the inferior alveolar nerve and facial nerve and diffuse widening of the mandibular canal. The objective of this case report is to enumerate the significance of perineural invasion in determining the course of the disease and necessitate the need for future studies that can shed light on molecular mediators and pathogenesis of perineural spread.

UR - http://www.scopus.com/inward/record.url?scp=85006162943&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006162943&partnerID=8YFLogxK

U2 - 10.1155/2016/3010934

DO - 10.1155/2016/3010934

M3 - Article

VL - 2016

JO - Case Reports in Dentistry

JF - Case Reports in Dentistry

SN - 2090-6447

M1 - 3010934

ER -