Mantle cell lymphoma of the palatine tonsil: A rare case report

Ranjitha Rao, Deviprasad Dosemane, Bhagyashree Jaipuria, Debarshi Saha, Manisha Narayan, Kanishka S. Rao

Research output: Contribution to journalArticle

Abstract

Introduction: Primary mantle cell lymphoma (MCL) of the palatine tonsil without involvement of the regional lymph nodes is rarely reported. Case Report: A 52-year-old male presented with complaints of a change in his voice over 3 months, with neither sore throat nor fever. Physical examination revealed right-sided grade IV and left-sided grade III tonsillar enlargement with prominent vessels. The patient underwent bilateral tonsillectomy. An initial histopathological report revealed chronic tonsillitis on the left side and suspicion of atypical lymphoproliferative disorder on the right. Immunohistochemically, the neoplastic cells were positive for Bcl2, CD20, CD5 and Cyclin D1 and negative for CD10, Bcl6 and CD3; thus a diagnosis of MCL was confirmed. Conclusion: MCL of the tonsil is rare. The microscopic diagnosis is challenging as the picture is very similar compared with other types of small cell lymphomas. A detailed immunohistochemistry panel is required for an accurate diagnosis.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalIranian Journal of Otorhinolaryngology
Volume30
Issue number5
DOIs
Publication statusPublished - 01-01-2018

Fingerprint

Mantle-Cell Lymphoma
Palatine Tonsil
Tonsillitis
Tonsillectomy
Lymphoproliferative Disorders
Pharyngitis
Cyclin D1
B-Cell Chronic Lymphocytic Leukemia
Physical Examination
Fever
Lymph Nodes
Immunohistochemistry

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Rao, R., Dosemane, D., Jaipuria, B., Saha, D., Narayan, M., & Rao, K. S. (2018). Mantle cell lymphoma of the palatine tonsil: A rare case report. Iranian Journal of Otorhinolaryngology, 30(5), 297-300. https://doi.org/10.22038/ijorl.2017.23400.1774
Rao, Ranjitha ; Dosemane, Deviprasad ; Jaipuria, Bhagyashree ; Saha, Debarshi ; Narayan, Manisha ; Rao, Kanishka S. / Mantle cell lymphoma of the palatine tonsil : A rare case report. In: Iranian Journal of Otorhinolaryngology. 2018 ; Vol. 30, No. 5. pp. 297-300.
@article{6b680cef6d9c49d4949271f0d1fc133d,
title = "Mantle cell lymphoma of the palatine tonsil: A rare case report",
abstract = "Introduction: Primary mantle cell lymphoma (MCL) of the palatine tonsil without involvement of the regional lymph nodes is rarely reported. Case Report: A 52-year-old male presented with complaints of a change in his voice over 3 months, with neither sore throat nor fever. Physical examination revealed right-sided grade IV and left-sided grade III tonsillar enlargement with prominent vessels. The patient underwent bilateral tonsillectomy. An initial histopathological report revealed chronic tonsillitis on the left side and suspicion of atypical lymphoproliferative disorder on the right. Immunohistochemically, the neoplastic cells were positive for Bcl2, CD20, CD5 and Cyclin D1 and negative for CD10, Bcl6 and CD3; thus a diagnosis of MCL was confirmed. Conclusion: MCL of the tonsil is rare. The microscopic diagnosis is challenging as the picture is very similar compared with other types of small cell lymphomas. A detailed immunohistochemistry panel is required for an accurate diagnosis.",
author = "Ranjitha Rao and Deviprasad Dosemane and Bhagyashree Jaipuria and Debarshi Saha and Manisha Narayan and Rao, {Kanishka S.}",
year = "2018",
month = "1",
day = "1",
doi = "10.22038/ijorl.2017.23400.1774",
language = "English",
volume = "30",
pages = "297--300",
journal = "Iranian Journal of Otorhinolaryngology",
issn = "2251-7251",
publisher = "Mashhad University of Medical Sciences",
number = "5",

}

Rao, R, Dosemane, D, Jaipuria, B, Saha, D, Narayan, M & Rao, KS 2018, 'Mantle cell lymphoma of the palatine tonsil: A rare case report', Iranian Journal of Otorhinolaryngology, vol. 30, no. 5, pp. 297-300. https://doi.org/10.22038/ijorl.2017.23400.1774

Mantle cell lymphoma of the palatine tonsil : A rare case report. / Rao, Ranjitha; Dosemane, Deviprasad; Jaipuria, Bhagyashree; Saha, Debarshi; Narayan, Manisha; Rao, Kanishka S.

In: Iranian Journal of Otorhinolaryngology, Vol. 30, No. 5, 01.01.2018, p. 297-300.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Mantle cell lymphoma of the palatine tonsil

T2 - A rare case report

AU - Rao, Ranjitha

AU - Dosemane, Deviprasad

AU - Jaipuria, Bhagyashree

AU - Saha, Debarshi

AU - Narayan, Manisha

AU - Rao, Kanishka S.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Introduction: Primary mantle cell lymphoma (MCL) of the palatine tonsil without involvement of the regional lymph nodes is rarely reported. Case Report: A 52-year-old male presented with complaints of a change in his voice over 3 months, with neither sore throat nor fever. Physical examination revealed right-sided grade IV and left-sided grade III tonsillar enlargement with prominent vessels. The patient underwent bilateral tonsillectomy. An initial histopathological report revealed chronic tonsillitis on the left side and suspicion of atypical lymphoproliferative disorder on the right. Immunohistochemically, the neoplastic cells were positive for Bcl2, CD20, CD5 and Cyclin D1 and negative for CD10, Bcl6 and CD3; thus a diagnosis of MCL was confirmed. Conclusion: MCL of the tonsil is rare. The microscopic diagnosis is challenging as the picture is very similar compared with other types of small cell lymphomas. A detailed immunohistochemistry panel is required for an accurate diagnosis.

AB - Introduction: Primary mantle cell lymphoma (MCL) of the palatine tonsil without involvement of the regional lymph nodes is rarely reported. Case Report: A 52-year-old male presented with complaints of a change in his voice over 3 months, with neither sore throat nor fever. Physical examination revealed right-sided grade IV and left-sided grade III tonsillar enlargement with prominent vessels. The patient underwent bilateral tonsillectomy. An initial histopathological report revealed chronic tonsillitis on the left side and suspicion of atypical lymphoproliferative disorder on the right. Immunohistochemically, the neoplastic cells were positive for Bcl2, CD20, CD5 and Cyclin D1 and negative for CD10, Bcl6 and CD3; thus a diagnosis of MCL was confirmed. Conclusion: MCL of the tonsil is rare. The microscopic diagnosis is challenging as the picture is very similar compared with other types of small cell lymphomas. A detailed immunohistochemistry panel is required for an accurate diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=85052704913&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052704913&partnerID=8YFLogxK

U2 - 10.22038/ijorl.2017.23400.1774

DO - 10.22038/ijorl.2017.23400.1774

M3 - Article

AN - SCOPUS:85052704913

VL - 30

SP - 297

EP - 300

JO - Iranian Journal of Otorhinolaryngology

JF - Iranian Journal of Otorhinolaryngology

SN - 2251-7251

IS - 5

ER -