Mastication frequency and postprandial blood sugar levels in normoglycaemic and dysglycaemic individuals: A cross-sectional comparative study

Vinayakm Adhu, Arun Shirali, Priyanka Niwas Pawaskarz, Deepak Madi, Nithyananda Chowta, John Thomas Ramapuram

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Introduction: Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results. Aim: To evaluate effects of mastication on postprandial blood glucose levels. Materials and methods: We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in cross-sectional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups. Results: In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl). Conclusion: In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.

Original languageEnglish
Pages (from-to)6-8
Number of pages3
JournalJournal of Clinical and Diagnostic Research
Issue number7
Publication statusPublished - 01-07-2016


All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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