Medicinal plants used in the treatment of human immunodeficiency virus

Bahare Salehi, Nanjangud V. Anil Kumar, Bilge Şener, Mehdi Sharifi-Rad, Mehtap Kılıç, Gail B. Mahady, Sanja Vlaisavljevic, Marcello Iriti, Farzad Kobarfard, William N. Setzer, Seyed Abdulmajid Ayatollahi, Athar Ata, Javad Sharifi-Rad

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33 Citations (Scopus)

Abstract

Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

Original languageEnglish
Article number1459
JournalInternational Journal of Molecular Sciences
Volume19
Issue number5
DOIs
Publication statusPublished - 14-05-2018

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Salehi, B., Anil Kumar, N. V., Şener, B., Sharifi-Rad, M., Kılıç, M., Mahady, G. B., Vlaisavljevic, S., Iriti, M., Kobarfard, F., Setzer, W. N., Ayatollahi, S. A., Ata, A., & Sharifi-Rad, J. (2018). Medicinal plants used in the treatment of human immunodeficiency virus. International Journal of Molecular Sciences, 19(5), [1459]. https://doi.org/10.3390/ijms19051459