Medicinal plants used in the treatment of human immunodeficiency virus

Bahare Salehi, Nanjangud V. Anil Kumar, Bilge Şener, Mehdi Sharifi-Rad, Mehtap Kılıç, Gail B. Mahady, Sanja Vlaisavljevic, Marcello Iriti, Farzad Kobarfard, William N. Setzer, Seyed Abdulmajid Ayatollahi, Athar Ata, Javad Sharifi-Rad

Research output: Contribution to journalReview article

29 Citations (Scopus)

Abstract

Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

Original languageEnglish
Article number1459
JournalInternational Journal of Molecular Sciences
Volume19
Issue number5
DOIs
Publication statusPublished - 14-05-2018

Fingerprint

human immunodeficiency virus
Medicinal Plants
Viruses
HIV
drugs
Chemotherapy
Therapeutics
chemotherapy
Pharmaceutical Preparations
Arsenals
Drug Therapy
Africa South of the Sahara
supplements
Biological Products
medicine
Drug Resistance
Medicine
emerging
resources

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Salehi, B., Anil Kumar, N. V., Şener, B., Sharifi-Rad, M., Kılıç, M., Mahady, G. B., ... Sharifi-Rad, J. (2018). Medicinal plants used in the treatment of human immunodeficiency virus. International Journal of Molecular Sciences, 19(5), [1459]. https://doi.org/10.3390/ijms19051459
Salehi, Bahare ; Anil Kumar, Nanjangud V. ; Şener, Bilge ; Sharifi-Rad, Mehdi ; Kılıç, Mehtap ; Mahady, Gail B. ; Vlaisavljevic, Sanja ; Iriti, Marcello ; Kobarfard, Farzad ; Setzer, William N. ; Ayatollahi, Seyed Abdulmajid ; Ata, Athar ; Sharifi-Rad, Javad. / Medicinal plants used in the treatment of human immunodeficiency virus. In: International Journal of Molecular Sciences. 2018 ; Vol. 19, No. 5.
@article{0895a057ae6f4faa8c1b7e8ccf7fbd1a,
title = "Medicinal plants used in the treatment of human immunodeficiency virus",
abstract = "Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.",
author = "Bahare Salehi and {Anil Kumar}, {Nanjangud V.} and Bilge Şener and Mehdi Sharifi-Rad and Mehtap Kılı{\cc} and Mahady, {Gail B.} and Sanja Vlaisavljevic and Marcello Iriti and Farzad Kobarfard and Setzer, {William N.} and Ayatollahi, {Seyed Abdulmajid} and Athar Ata and Javad Sharifi-Rad",
year = "2018",
month = "5",
day = "14",
doi = "10.3390/ijms19051459",
language = "English",
volume = "19",
journal = "International Journal of Molecular Sciences",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "5",

}

Salehi, B, Anil Kumar, NV, Şener, B, Sharifi-Rad, M, Kılıç, M, Mahady, GB, Vlaisavljevic, S, Iriti, M, Kobarfard, F, Setzer, WN, Ayatollahi, SA, Ata, A & Sharifi-Rad, J 2018, 'Medicinal plants used in the treatment of human immunodeficiency virus', International Journal of Molecular Sciences, vol. 19, no. 5, 1459. https://doi.org/10.3390/ijms19051459

Medicinal plants used in the treatment of human immunodeficiency virus. / Salehi, Bahare; Anil Kumar, Nanjangud V.; Şener, Bilge; Sharifi-Rad, Mehdi; Kılıç, Mehtap; Mahady, Gail B.; Vlaisavljevic, Sanja; Iriti, Marcello; Kobarfard, Farzad; Setzer, William N.; Ayatollahi, Seyed Abdulmajid; Ata, Athar; Sharifi-Rad, Javad.

In: International Journal of Molecular Sciences, Vol. 19, No. 5, 1459, 14.05.2018.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Medicinal plants used in the treatment of human immunodeficiency virus

AU - Salehi, Bahare

AU - Anil Kumar, Nanjangud V.

AU - Şener, Bilge

AU - Sharifi-Rad, Mehdi

AU - Kılıç, Mehtap

AU - Mahady, Gail B.

AU - Vlaisavljevic, Sanja

AU - Iriti, Marcello

AU - Kobarfard, Farzad

AU - Setzer, William N.

AU - Ayatollahi, Seyed Abdulmajid

AU - Ata, Athar

AU - Sharifi-Rad, Javad

PY - 2018/5/14

Y1 - 2018/5/14

N2 - Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

AB - Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa. There have been very promising developments in the treatment of HIV with anti-retroviral drug cocktails. However, drug resistance to anti-HIV drugs is emerging, and many people infected with HIV have adverse reactions or do not have ready access to currently available HIV chemotherapies. Thus, there is a need to discover new anti-HIV agents to supplement our current arsenal of anti-HIV drugs and to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies. Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines, including anti-HIV agents. This review presents a survey of plants that have shown anti-HIV activity, both in vitro and in vivo.

UR - http://www.scopus.com/inward/record.url?scp=85047056765&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047056765&partnerID=8YFLogxK

U2 - 10.3390/ijms19051459

DO - 10.3390/ijms19051459

M3 - Review article

VL - 19

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 5

M1 - 1459

ER -