Melioidosis: Reinfection going incognito as relapse

Isra Halim, Tushar Shaw, Chaitanya Tellapragada, K. Vandana, Chiranjay Mukhopadhyay

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Melioidosis has recently gained importance as an emerging disease in India. Recurrent melioidosis has been reported from different parts of the world and can be due to relapse or reinfection. Distinction between relapse and reinfection is important for epidemiology, investigation and management. Here, we present the data regarding rate of recurrence and utility of multilocus sequence typing (MLST) in differentiating relapse form reinfection amongst melioidosis patients from a tertiary care hospital in South India. Amongst the 31 patients who survived and underwent follow-up, 4 (13%) presented with recurrence. Three cases (75%) were identified as reinfection and one (25%) as relapse based on MLST. Re-exposure to environmental Burkholderia pseudomallei amongst patients with melioidosis in endemic areas is likely. In such a scenario, more often than not, recurrence of melioidosis can be attributed to reinfection.

Original languageEnglish
Pages (from-to)593-596
Number of pages4
JournalIndian Journal of Medical Microbiology
Volume35
Issue number4
DOIs
Publication statusPublished - 01-10-2017

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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