Microsatellite-based phylogeny of Indian domestic goats

Pramod K. Rout, Manjunath B. Joshi, Ajoy Mandal, Denis Laloe, Lalji Singh, Kumarasamy Thangaraj

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Background: The domestic goat is one of the important livestock species of India. In the present study we assess genetic diversity of Indian goats using 17 microsatellite markers. Breeds were sampled from their natural habitat, covering different agroclimatic zones. Results: The mean number of alleles per locus (NA) ranged from 8.1 in Barbari to 9.7 in Jakhrana goats. The mean expected heterozygosity (He) ranged from 0.739 in Barbari to 0.783 in Jakhrana goats. Deviations from Hardy-Weinberg Equilibrium (HWE) were statistically significant (P < 0.05) for 5 loci breed combinations. The DA measure of genetic distance between pairs of breeds indicated that the lowest distance was between Marwari and Sirohi (0.135). The highest distance was between Pashmina and Black Bengal. An analysis of molecular variance indicated that 6.59% of variance exists among the Indian goat breeds. Both a phylogenetic tree and Principal Component Analysis showed the distribution of breeds in two major clusters with respect to their geographic distribution. Conclusion: Our study concludes that Indian goat populations can be classified into distinct genetic groups or breeds based on the microsatellites as well as mtDNA information.

Original languageEnglish
Article number11
JournalBMC Genetics
Volume9
DOIs
Publication statusPublished - 28-01-2008

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Phylogeny
Goats
Microsatellite Repeats
Livestock
Principal Component Analysis
Mitochondrial DNA
Ecosystem
India
Analysis of Variance
Alleles
Population

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Cite this

Rout, P. K., Joshi, M. B., Mandal, A., Laloe, D., Singh, L., & Thangaraj, K. (2008). Microsatellite-based phylogeny of Indian domestic goats. BMC Genetics, 9, [11]. https://doi.org/10.1186/1471-2156-9-11
Rout, Pramod K. ; Joshi, Manjunath B. ; Mandal, Ajoy ; Laloe, Denis ; Singh, Lalji ; Thangaraj, Kumarasamy. / Microsatellite-based phylogeny of Indian domestic goats. In: BMC Genetics. 2008 ; Vol. 9.
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Rout, PK, Joshi, MB, Mandal, A, Laloe, D, Singh, L & Thangaraj, K 2008, 'Microsatellite-based phylogeny of Indian domestic goats', BMC Genetics, vol. 9, 11. https://doi.org/10.1186/1471-2156-9-11

Microsatellite-based phylogeny of Indian domestic goats. / Rout, Pramod K.; Joshi, Manjunath B.; Mandal, Ajoy; Laloe, Denis; Singh, Lalji; Thangaraj, Kumarasamy.

In: BMC Genetics, Vol. 9, 11, 28.01.2008.

Research output: Contribution to journalArticle

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