Abstract
Cyclophosphamide induced a depletion in liver glutathione (GSH) and high rate of lipid peroxidation. GSH depletion was evident from 20 min onwards and the maximum depletion was observed at 3 hr post treatment. Lipid peroxidation was significant only after the maximum depletion of GSH. Pretreatment with either MRC or WR-77913 individually, or in combination could prevent the depletion of GSH and induction of lipid peroxidation after cyclophosphamide treatment.
Original language | English |
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Pages (from-to) | 562-564 |
Number of pages | 3 |
Journal | Indian Journal of Experimental Biology |
Volume | 32 |
Issue number | 8 |
Publication status | Published - 01-01-1994 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Medicine(all)
- Molecular Biology
- Cell Biology