Modulatory effect of 900 MHz radiation on biochemical and reproductive parameters in rats

S. N. Narayanan, S. T. Lukose, G. Arun, N. Mohapatra, J. Pamala, P. L. Concessao, R. Jetti, V. Kedage, K. Nalini, P. Gopalakrishna Bhat

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the present study, the effect of 900 MHz radiation exposure on blood biochemical and reproductive parameters was evaluated in adolescent rats. Male albino Wistar rats (8-10 weeks of age) were exposed to 900 MHz radiation (1hr/day, power density - 146.60 μW/cm2) from a mobile phone for 28 days. On 29th day the animals were euthanized and malondialdehyde (MDA), total antioxidants (TA) levels and Glutathione-S transferase (GST) activity were studied in the blood. Reproductive parameters such as total sperm count, percentage of non-motile sperms, and sperm morphology were determined. Testes sections were stained with H & E staining and their cellular integrity was evaluated. Caspase-3 activity in the testes was also determined. MDA concentration was increased but TA levels and GST activity were not found to be different in 900 MHz group compared to controls. Sperm motility was found to be slightly reduced in 900 MHz group. Percentage of abnormal sperm was significantly elevated in 900 MHz group. Additionally, loss of germ cells particularly spermatocytes and spermatids was found in the testes of 900 MHz group. Testes caspase-3 activity was slightly elevated in 900 MHz exposed rats. Chronic 900 MHz exposure induced oxidative damage in the blood and lead to alterations in reproductive parameters in rats.

Original languageEnglish
Pages (from-to)581-587
Number of pages7
JournalBratislava Medical Journal
Volume119
Issue number9
DOIs
Publication statusPublished - 01-01-2018

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Testis
Radiation
Spermatozoa
Glutathione Transferase
Malondialdehyde
Caspase 3
Antioxidants
Cell Phones
Spermatocytes
Sperm Count
Spermatids
Sperm Motility
Germ Cells
Wistar Rats
Staining and Labeling

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Narayanan, S. N., Lukose, S. T., Arun, G., Mohapatra, N., Pamala, J., Concessao, P. L., ... Gopalakrishna Bhat, P. (2018). Modulatory effect of 900 MHz radiation on biochemical and reproductive parameters in rats. Bratislava Medical Journal, 119(9), 581-587. https://doi.org/10.4149/BLL_2018_105
Narayanan, S. N. ; Lukose, S. T. ; Arun, G. ; Mohapatra, N. ; Pamala, J. ; Concessao, P. L. ; Jetti, R. ; Kedage, V. ; Nalini, K. ; Gopalakrishna Bhat, P. / Modulatory effect of 900 MHz radiation on biochemical and reproductive parameters in rats. In: Bratislava Medical Journal. 2018 ; Vol. 119, No. 9. pp. 581-587.
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Narayanan, SN, Lukose, ST, Arun, G, Mohapatra, N, Pamala, J, Concessao, PL, Jetti, R, Kedage, V, Nalini, K & Gopalakrishna Bhat, P 2018, 'Modulatory effect of 900 MHz radiation on biochemical and reproductive parameters in rats', Bratislava Medical Journal, vol. 119, no. 9, pp. 581-587. https://doi.org/10.4149/BLL_2018_105

Modulatory effect of 900 MHz radiation on biochemical and reproductive parameters in rats. / Narayanan, S. N.; Lukose, S. T.; Arun, G.; Mohapatra, N.; Pamala, J.; Concessao, P. L.; Jetti, R.; Kedage, V.; Nalini, K.; Gopalakrishna Bhat, P.

In: Bratislava Medical Journal, Vol. 119, No. 9, 01.01.2018, p. 581-587.

Research output: Contribution to journalArticle

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AU - Lukose, S. T.

AU - Arun, G.

AU - Mohapatra, N.

AU - Pamala, J.

AU - Concessao, P. L.

AU - Jetti, R.

AU - Kedage, V.

AU - Nalini, K.

AU - Gopalakrishna Bhat, P.

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