Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs

Namdev Dhas, Ritu Kudarha, Atul Garkal, Vivek Ghate, Shilpa Sharma, Prabhakar Panzade, Shubham Khot, Pinal Chaudhari, Ashutosh Singh, Mitali Paryani, Shaila Lewis, Neha Garg, Narinder Singh, Priyanka Bangar, Tejal Mehta

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)

Abstract

In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.

Original languageEnglish
Pages (from-to)257-283
Number of pages27
JournalJournal of Controlled Release
Volume330
DOIs
Publication statusPublished - 10-02-2021

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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