The Artificial Neural Network (ANN) with small size may not solve the problem while the network with large size will suffer from poor generalization. The pruning methods are approaches for finding appropriate size of the network by eliminating few parameters from the network. The sensitivity based pruning will determine sensitivity of the network error for removal of a parameter and eliminate parameters with least sensitivity. In this research a sensitivity based pruning method is integrated with multilayer feed-forward ANN and applied on MNIST handwritten numeral recognition. An analysis of effect of pruning on the network is compared with performance of a network without pruning. It is observed that the network integrated with pruning method show better generalization ability than a network without pruning method being incorporated.