Multiple autoimmune syndrome with isotopic phenomenon: Association of lichen planus, vitiligo and alopecia areata with autoimmune hepatitis

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Multiple autoimmune syndrome (MAS) is the presence of 3 or more autoimmune disorders in the same patient, and is being increasingly reported. Here, we report a 31-year-old man who presented with lichen planus, vitiligo, alopecia areata and hepatitis. He also displayed isotopic phenomenon in the form of depigmented lichen planus lesions. Autoimmune tautology is implicated as the basis for MAS, and is supported by the findings of polyautoimmunity and familial immunity in cross-sectional studies. There are reports of dermatological and systemic autoimmune diseases co-occurring as MAS.

Original languageEnglish
Pages (from-to)356-359
Number of pages4
JournalJournal of Pakistan Association of Dermatologists
Issue number3
Publication statusPublished - 01-01-2018


All Science Journal Classification (ASJC) codes

  • Dermatology

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