Multiple intracerebral lesions in a young male

Madi Deepak, Achappa Basavaprabhu, Mahalingam Soundarya

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: As the incidence of HIV infection has increased its neurological complications are being encountered in our clinical practice. Toxoplasmosis is a common cerebral opportunistic infection seen in HIV-infected patients, even though the incidence has declined with the use of antiretroviral therapy. Establishing a definitive diagnosis of cerebral toxoplasmosis is difficult in resource limited settings. Clinical case: A 20 year old gentleman was referred to our institute as a case of stroke. Magnetic resonance imaging (MRI) of his brain showed multiple ill-defined and nodular enhancing lesions in bilateral supratentorial and infratentorial neuroparenchyma. Test for HIV-1 was reactive. Toxoplasma serology revealed raised IgG antibody levels. Based on the MRI features and positive toxoplasma serology a diagnosis of cerebral toxoplasmosis was made. He was treated with trimethoprim/ sulfamethoxazole and pyrimethamine/ Sulfadoxine for 3 weeks. After 2 weeks of treatment, repeat MRI of brain was done which showed significant resolution of the lesions. Conclusion: We are presenting this case to highlight the fact that cerebral toxoplasmosis should be considered in the differential diagnosis of multiple neuroparenchymal lesions in young individuals who present with neurological deficits.

Original languageEnglish
Pages (from-to)1045-1048
Number of pages4
JournalAfrican Health Sciences
Volume15
Issue number3
DOIs
Publication statusPublished - 01-09-2015

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Cerebral Toxoplasmosis
Toxoplasma
Magnetic Resonance Imaging
Serology
Toxoplasmosis
Incidence
Opportunistic Infections
Sulfamethoxazole Drug Combination Trimethoprim
Brain
HIV Infections
HIV-1
Differential Diagnosis
Immunoglobulin G
Stroke
HIV
Antibodies
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Deepak, Madi ; Basavaprabhu, Achappa ; Soundarya, Mahalingam. / Multiple intracerebral lesions in a young male. In: African Health Sciences. 2015 ; Vol. 15, No. 3. pp. 1045-1048.
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Multiple intracerebral lesions in a young male. / Deepak, Madi; Basavaprabhu, Achappa; Soundarya, Mahalingam.

In: African Health Sciences, Vol. 15, No. 3, 01.09.2015, p. 1045-1048.

Research output: Contribution to journalArticle

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