Abstract

Paragangliomas are rare with multicentricity being more common in patients with familial history. Early recognition of the characteristic symptoms of headache, palpitations, and diaphoresis in a patient with hypertension and prompt appropriate intervention can minimize the morbidity associated with such tumors and prevent a potentially fatal outcome. Paragangliomas represent neoplasms of neural crest origin that arise from paraganglia. Paragangliomas are tumours arising in extra-adrenal paraganglia either in the paravertebral space. We report a rare case of two discrete paragangliomas in the retroperitoneum of a young girl presenting with throbbing headache. Contrast Enhanced CT Abdomen showed the lesions as a large irregular heterogeneous and intensely enhancing mass lesions. Elevated levels of vanillylmandelic acid were found in the Urine. The lesions were removed by surgery and the histopathologic findings of both the lesions confirmed the diagnosis of multiple paragangliomas. Early identification and early surgery will minimize the potential risks and complications in this condition.

Original languageEnglish
Pages (from-to)125-127
Number of pages3
JournalIndian Journal of Surgery
Volume75
Issue number1 SUPPL.
DOIs
Publication statusPublished - 01-10-2013

Fingerprint

Paraganglioma
Headache
Vanilmandelic Acid
Neoplasms
Fatal Outcome
Neural Crest
Abdomen
History
Urine
Hypertension
Morbidity

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Rai, Santosh ; Subas, K. ; Kini, J. ; Bhat, N. ; Rao, S. / Multiple retroperitoneal paragangliomas. In: Indian Journal of Surgery. 2013 ; Vol. 75, No. 1 SUPPL. pp. 125-127.
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Multiple retroperitoneal paragangliomas. / Rai, Santosh; Subas, K.; Kini, J.; Bhat, N.; Rao, S.

In: Indian Journal of Surgery, Vol. 75, No. 1 SUPPL., 01.10.2013, p. 125-127.

Research output: Contribution to journalArticle

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AB - Paragangliomas are rare with multicentricity being more common in patients with familial history. Early recognition of the characteristic symptoms of headache, palpitations, and diaphoresis in a patient with hypertension and prompt appropriate intervention can minimize the morbidity associated with such tumors and prevent a potentially fatal outcome. Paragangliomas represent neoplasms of neural crest origin that arise from paraganglia. Paragangliomas are tumours arising in extra-adrenal paraganglia either in the paravertebral space. We report a rare case of two discrete paragangliomas in the retroperitoneum of a young girl presenting with throbbing headache. Contrast Enhanced CT Abdomen showed the lesions as a large irregular heterogeneous and intensely enhancing mass lesions. Elevated levels of vanillylmandelic acid were found in the Urine. The lesions were removed by surgery and the histopathologic findings of both the lesions confirmed the diagnosis of multiple paragangliomas. Early identification and early surgery will minimize the potential risks and complications in this condition.

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