Multisystem langerhans cell histiocytosis in adult

Anubhav Garg, Pramod Kumar

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4 Citations (Scopus)

Abstract

Langerhans cell histiocytosis (LCH), is a rare disorder, clinically presents with heterogeneous manifestations, and has an unpredictable outcome. Commonly seen in infancy or early childhood, the disorder is characterized by proliferation of abnormal and clonal Langerhans cell in skin, bone, lymph nodes, lungs, liver, spleen, and bone marrow. Occurrence of LCH in adults is rare. Here, we report the case of an adult with acute onset of polymorphic eruptions all over the body, which on biopsy showed features of multisystem LCH, and was confirmed by immunohistochemistry. Although multisystem LCH has a poor prognosis, our patient responded well to chemotherapy.

Original languageEnglish
Pages (from-to)58-60
Number of pages3
JournalIndian Journal of Dermatology
Volume57
Issue number1
DOIs
Publication statusPublished - 01-01-2012

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All Science Journal Classification (ASJC) codes

  • Dermatology

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