Abstract
The title compound {systematic name: methyl 2-[(2′-cyanobiphenyl-4-yl)methylammonio]-3-methylbutanoate chloride), C20H23N2O2+·Cl-, is a key intermediate in the synthesis of valsartan. It crystallizes with two ion pairs in the asymmetric unit, related pseudocentrosymmetrically to each other. The two cations differ only in the orientation of the isopropyl group.
| Original language | English |
|---|---|
| Journal | Acta Crystallographica Section E: Structure Reports Online |
| Volume | 60 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 11-2004 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Materials Science(all)
- Condensed Matter Physics
Cite this
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N-[(2′-cyanobiphenyl-4-yl)methyl]-L-valine methyl ester hydrochloride : An intermediate in the synthesis of valsartan. / Yathirajan, Hemmige S.; Nagaraj, Basavegowda; Gaonkar, Santhosh L.; Narasegowda, Rajenahally S.; Nagaraja, Padmarajaiah; Prabhuswamy, Basappa; Bolte, Michael.
In: Acta Crystallographica Section E: Structure Reports Online, Vol. 60, No. 11, 11.2004.Research output: Contribution to journal › Article
TY - JOUR
T1 - N-[(2′-cyanobiphenyl-4-yl)methyl]-L-valine methyl ester hydrochloride
T2 - An intermediate in the synthesis of valsartan
AU - Yathirajan, Hemmige S.
AU - Nagaraj, Basavegowda
AU - Gaonkar, Santhosh L.
AU - Narasegowda, Rajenahally S.
AU - Nagaraja, Padmarajaiah
AU - Prabhuswamy, Basappa
AU - Bolte, Michael
PY - 2004/11
Y1 - 2004/11
N2 - The title compound {systematic name: methyl 2-[(2′-cyanobiphenyl-4-yl)methylammonio]-3-methylbutanoate chloride), C20H23N2O2+·Cl-, is a key intermediate in the synthesis of valsartan. It crystallizes with two ion pairs in the asymmetric unit, related pseudocentrosymmetrically to each other. The two cations differ only in the orientation of the isopropyl group.
AB - The title compound {systematic name: methyl 2-[(2′-cyanobiphenyl-4-yl)methylammonio]-3-methylbutanoate chloride), C20H23N2O2+·Cl-, is a key intermediate in the synthesis of valsartan. It crystallizes with two ion pairs in the asymmetric unit, related pseudocentrosymmetrically to each other. The two cations differ only in the orientation of the isopropyl group.
UR - http://www.scopus.com/inward/record.url?scp=18544389506&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=18544389506&partnerID=8YFLogxK
U2 - 10.1107/S1600536804026790
DO - 10.1107/S1600536804026790
M3 - Article
AN - SCOPUS:18544389506
VL - 60
JO - Acta Crystallographica Section E: Structure Reports Online
JF - Acta Crystallographica Section E: Structure Reports Online
SN - 1600-5368
IS - 11
ER -