Nanocrystals

A newer technological advancement in drug delivery

Neha Xalxo, Anup Naha, Abhishek Dhoot, Juhi Priya

Research output: Contribution to journalReview article

Abstract

Solubility is defined as dissolution of a solute in a solvent to give a homogenous system. It is an important consideration which is required to achieve appropriate drug concentration in systemic circulation for a chosen pharmacological response. With innovation in technologies, the discoveries of drugs having better efficacy are restricted due to poor solubility, despite having clinical efficacy. Hence it has become a major challenge. More than 50% new chemical entities produced in pharmacy industry are practically insoluble in water. Nano crystals have potential to overcome this issue. They have size in nanometer range (mean diameter < 1000nm) which changes the drug properties dramatically. This review article summaries different methods of preparation, various production technologies available currently in industries; evaluation techniques, applications of nano crystal formulation, future trends and challenges of nano crystal formulation, and various marketed dosage forms developed using nano crystals are discussed.

Original languageEnglish
Pages (from-to)1685-1690
Number of pages6
JournalResearch Journal of Pharmacy and Technology
Volume11
Issue number4
DOIs
Publication statusPublished - 01-04-2018

Fingerprint

Nanoparticles
Solubility
Industry
Technology
Dosage Forms
Drug Discovery
Pharmaceutical Preparations
Pharmacology
Water

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
  • Pharmacology (medical)

Cite this

Xalxo, Neha ; Naha, Anup ; Dhoot, Abhishek ; Priya, Juhi. / Nanocrystals : A newer technological advancement in drug delivery. In: Research Journal of Pharmacy and Technology. 2018 ; Vol. 11, No. 4. pp. 1685-1690.
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Nanocrystals : A newer technological advancement in drug delivery. / Xalxo, Neha; Naha, Anup; Dhoot, Abhishek; Priya, Juhi.

In: Research Journal of Pharmacy and Technology, Vol. 11, No. 4, 01.04.2018, p. 1685-1690.

Research output: Contribution to journalReview article

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