Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15

S. Govindan, B. Chakrakodi, S. Prabhakara, G. Arakere, S. Kumar, I. Bairy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We report a case of necrotizing fasciitis (NF), caused by community-acquired epidemic methicillin resistant Staphylococcus aureus 15 (EMRSA 15). The patient had a prolonged recovery period following treatment with antibiotics and surgical debridement of the infected part. Molecular characterization revealed that the isolate carried Staphylococcal Cassette Chromosome mec (SCC mec) type IV harboring Panton-Valentine Leucocidin (pvl) gene and having accessory gene regulator (agr) type I. The isolate was positive for enterotoxin gene cluster (egc). Pulsed field gel electrophoresis patterns revealed that the isolate belonged sequence type 22, which is an Indian variant of EMRSA 15, reported earlier.

Original languageEnglish
Pages (from-to)476-479
Number of pages4
JournalIndian Journal of Medical Microbiology
Volume30
Issue number4
DOIs
Publication statusPublished - 01-10-2012

Fingerprint

Necrotizing Fasciitis
Methicillin-Resistant Staphylococcus aureus
Pulsed Field Gel Electrophoresis
Enterotoxins
Debridement
Regulator Genes
Multigene Family
Chromosomes
Anti-Bacterial Agents
Genes
Therapeutics
Panton-Valentine leukocidin

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

@article{c750705163e742d79313de68d1a2cbeb,
title = "Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15",
abstract = "We report a case of necrotizing fasciitis (NF), caused by community-acquired epidemic methicillin resistant Staphylococcus aureus 15 (EMRSA 15). The patient had a prolonged recovery period following treatment with antibiotics and surgical debridement of the infected part. Molecular characterization revealed that the isolate carried Staphylococcal Cassette Chromosome mec (SCC mec) type IV harboring Panton-Valentine Leucocidin (pvl) gene and having accessory gene regulator (agr) type I. The isolate was positive for enterotoxin gene cluster (egc). Pulsed field gel electrophoresis patterns revealed that the isolate belonged sequence type 22, which is an Indian variant of EMRSA 15, reported earlier.",
author = "S. Govindan and B. Chakrakodi and S. Prabhakara and G. Arakere and S. Kumar and I. Bairy",
year = "2012",
month = "10",
day = "1",
doi = "10.4103/0255-0857.103778",
language = "English",
volume = "30",
pages = "476--479",
journal = "Indian Journal of Medical Microbiology",
issn = "0255-0857",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "4",

}

Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15. / Govindan, S.; Chakrakodi, B.; Prabhakara, S.; Arakere, G.; Kumar, S.; Bairy, I.

In: Indian Journal of Medical Microbiology, Vol. 30, No. 4, 01.10.2012, p. 476-479.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15

AU - Govindan, S.

AU - Chakrakodi, B.

AU - Prabhakara, S.

AU - Arakere, G.

AU - Kumar, S.

AU - Bairy, I.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - We report a case of necrotizing fasciitis (NF), caused by community-acquired epidemic methicillin resistant Staphylococcus aureus 15 (EMRSA 15). The patient had a prolonged recovery period following treatment with antibiotics and surgical debridement of the infected part. Molecular characterization revealed that the isolate carried Staphylococcal Cassette Chromosome mec (SCC mec) type IV harboring Panton-Valentine Leucocidin (pvl) gene and having accessory gene regulator (agr) type I. The isolate was positive for enterotoxin gene cluster (egc). Pulsed field gel electrophoresis patterns revealed that the isolate belonged sequence type 22, which is an Indian variant of EMRSA 15, reported earlier.

AB - We report a case of necrotizing fasciitis (NF), caused by community-acquired epidemic methicillin resistant Staphylococcus aureus 15 (EMRSA 15). The patient had a prolonged recovery period following treatment with antibiotics and surgical debridement of the infected part. Molecular characterization revealed that the isolate carried Staphylococcal Cassette Chromosome mec (SCC mec) type IV harboring Panton-Valentine Leucocidin (pvl) gene and having accessory gene regulator (agr) type I. The isolate was positive for enterotoxin gene cluster (egc). Pulsed field gel electrophoresis patterns revealed that the isolate belonged sequence type 22, which is an Indian variant of EMRSA 15, reported earlier.

UR - http://www.scopus.com/inward/record.url?scp=84871304167&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871304167&partnerID=8YFLogxK

U2 - 10.4103/0255-0857.103778

DO - 10.4103/0255-0857.103778

M3 - Article

C2 - 23183478

AN - SCOPUS:84871304167

VL - 30

SP - 476

EP - 479

JO - Indian Journal of Medical Microbiology

JF - Indian Journal of Medical Microbiology

SN - 0255-0857

IS - 4

ER -