Neurogenic appendicopathy - Role of enterochromaffin cells in its pathogenesis

Ramdas Naik, Poornima Baliga, Muktha Ramesh Pai

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One hundred cases of neurogenic appendicopathy were histochemically studied for schwann cells and enterochromaffin cells. The early phase, labelled as neuroappendicopathy (29 cases) showed minimum to moderate number of extraepithelial enterochromaffin cells without neurogenous hyperplasia. In 53 cases, there was intra and submucosal neural hyperplasia with increase in the extraepithelial enterochromaffin cells, representing the active phase.The late phase known as obliterative neurogenic appendicopathy, showed extraepithelial enterochromaffin cells and schwann cell proliferation of variable grades (18 cases). The origin of extraepithelial enterochromaffin cells is related to proliferating nerve plexus, rather than epithelial enterochromaffin cells.

Original languageEnglish
Pages (from-to)279-281
Number of pages3
JournalIndian Journal of Pathology and Microbiology
Issue number3
Publication statusPublished - 07-1999


All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Microbiology (medical)

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