New benzoxazoles as potential antitumor agents

S.G. Kini, G. Saraswat, A.M. Gandhi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.
Original languageEnglish
Pages (from-to)99-100
Number of pages2
JournalIndian Journal of Heterocyclic Chemistry
Volume15
Issue number1
Publication statusPublished - 2005

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Benzoxazoles
Antineoplastic Agents
Screening
Benzoates
Cisplatin
Pharmaceutical Preparations

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Kini, S.G. ; Saraswat, G. ; Gandhi, A.M. / New benzoxazoles as potential antitumor agents. In: Indian Journal of Heterocyclic Chemistry. 2005 ; Vol. 15, No. 1. pp. 99-100.
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note = "Cited By :2 Export Date: 10 November 2017 Correspondence Address: Kini, S.G.; Department of Chemistry, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India References: (2000) Chem. Abstr., pp. 265194s; Hill, R.P., Kallman, R.F., (1987) Experimental Cancer Therapy, p. 114; Meyer, B.H., Ferrigni, N.R., McLaughlin, J.L., (1982) Planta Med., 45, p. 31; Ghosh, M.N., (1984) Fundamentals of Experimental Pharmacology, p. 53. , Scientific Book Agency",
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Kini, SG, Saraswat, G & Gandhi, AM 2005, 'New benzoxazoles as potential antitumor agents', Indian Journal of Heterocyclic Chemistry, vol. 15, no. 1, pp. 99-100.

New benzoxazoles as potential antitumor agents. / Kini, S.G.; Saraswat, G.; Gandhi, A.M.

In: Indian Journal of Heterocyclic Chemistry, Vol. 15, No. 1, 2005, p. 99-100.

Research output: Contribution to journalArticle

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T1 - New benzoxazoles as potential antitumor agents

AU - Kini, S.G.

AU - Saraswat, G.

AU - Gandhi, A.M.

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AB - 2-Aryl benzoxazols were synthesized by refluxing o-aminophenol with substituted benzoic acids in the presence of polyphosphoric acid. The screening for antitumour activity was done as per the National Cancer Institute Drug Screening Strategy 1985. Three compounds were found to be significantly cytotoxic as compared to Cisplatin against the EAC induced mice.

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