Niosomal sumatriptan succinate for nasal administration

S. Gayathri Devi, Venkatesh, N. Udupa

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Niosomes of sumatriptan succinate were prepared using lipid hydration method. The prepared niosomes were evaluated for entrapment efficiency, size analysis and in vitro release studies. Further, the niosomes were evaluated for nasal absorption using an ex vivo animal model. The entrapment efficiency was found to be 57.9 ± 0.96 %.The niosomes released 58.71% of sumatriptan succinate over a period of 6 h and 78.1% of the drug was absorbed from the nasal mucosa ex vivo.

Original languageEnglish
Pages (from-to)479-481
Number of pages3
JournalIndian Journal of Pharmaceutical Sciences
Volume62
Issue number6
Publication statusPublished - 2000

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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