Nocardia farcinica pneumonia in chronic granulomatous disease

Kathleen M. Gutierrez, Avinash K. Shetty, Ann M. Arvin

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Infection with Nocardia poses a diagnostic challenge in patients with chronic granulomatous disease (CGD) because the signs and symptoms are often nonspecific, delay in diagnosis is common, and invasive procedures are frequently required to obtain appropriate tissue specimens. We present the first reported case of N farcinica pneumonia in an adolescent with X-linked CGD. Differentiation of N farcinica from other members of N asteroides complex is important because of its propensity for causing disseminated infection and antimicrobial resistance. Physicians caring for patients with CGD should maintain a high index of suspicion for nocardiosis, especially in those receiving chronic steroid therapy. Early diagnosis remains critical for decreased morbidity and occasional mortality.

Original languageEnglish
Pages (from-to)961-964
Number of pages4
JournalPediatrics
Volume104
Issue number4 I
DOIs
Publication statusPublished - 01-10-1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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