Ocular surface squamous neoplasia in Xeroderma pigmentosum

Rajesh R. Nayak, Gurudutt M. Kamath, Manjunath M. Kamath, Ajay R. Kamath, Susan D'Souza, Roopashree

Research output: Contribution to journalArticle

Abstract

Xeroderma pigmentosum (XP) is a rare genetic disorder associated with multiple oculocutaneous and neurological manifestations. It occurs due to deficiency of the enzymes responsible for repairing ultraviolet radiationinduced DNA damage. Persistence of un-repaired DNA results in somatic mutations, leading to neoplasia of the skin and ocular surface. As this condition is rare, only isolated case reports of XP with ocular surface squamous neoplasia (OSSN) are found in literature.

Original languageEnglish
Article number15
JournalOnline Journal of Health and Allied Sciences
Volume12
Issue number3
Publication statusPublished - 01-07-2013

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Xeroderma Pigmentosum
Inborn Genetic Diseases
Neurologic Manifestations
DNA Damage
Neoplasms
Skin
Mutation
DNA
Enzymes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Nayak, R. R., Kamath, G. M., Kamath, M. M., Kamath, A. R., D'Souza, S., & Roopashree (2013). Ocular surface squamous neoplasia in Xeroderma pigmentosum. Online Journal of Health and Allied Sciences, 12(3), [15].
Nayak, Rajesh R. ; Kamath, Gurudutt M. ; Kamath, Manjunath M. ; Kamath, Ajay R. ; D'Souza, Susan ; Roopashree. / Ocular surface squamous neoplasia in Xeroderma pigmentosum. In: Online Journal of Health and Allied Sciences. 2013 ; Vol. 12, No. 3.
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Nayak, RR, Kamath, GM, Kamath, MM, Kamath, AR, D'Souza, S & Roopashree 2013, 'Ocular surface squamous neoplasia in Xeroderma pigmentosum', Online Journal of Health and Allied Sciences, vol. 12, no. 3, 15.

Ocular surface squamous neoplasia in Xeroderma pigmentosum. / Nayak, Rajesh R.; Kamath, Gurudutt M.; Kamath, Manjunath M.; Kamath, Ajay R.; D'Souza, Susan; Roopashree.

In: Online Journal of Health and Allied Sciences, Vol. 12, No. 3, 15, 01.07.2013.

Research output: Contribution to journalArticle

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Nayak RR, Kamath GM, Kamath MM, Kamath AR, D'Souza S, Roopashree. Ocular surface squamous neoplasia in Xeroderma pigmentosum. Online Journal of Health and Allied Sciences. 2013 Jul 1;12(3). 15.