Ocular surface squamous neoplasia in Xeroderma pigmentosum

Rajesh R. Nayak, Gurudutt M. Kamath, Manjunath M. Kamath, Ajay R. Kamath, Susan D'Souza, Roopashree

Research output: Contribution to journalArticle

Abstract

Xeroderma pigmentosum (XP) is a rare genetic disorder associated with multiple oculocutaneous and neurological manifestations. It occurs due to deficiency of the enzymes responsible for repairing ultraviolet radiationinduced DNA damage. Persistence of un-repaired DNA results in somatic mutations, leading to neoplasia of the skin and ocular surface. As this condition is rare, only isolated case reports of XP with ocular surface squamous neoplasia (OSSN) are found in literature.

Original languageEnglish
Article number15
JournalOnline Journal of Health and Allied Sciences
Volume12
Issue number3
Publication statusPublished - 01-07-2013

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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  • Cite this

    Nayak, R. R., Kamath, G. M., Kamath, M. M., Kamath, A. R., D'Souza, S., & Roopashree (2013). Ocular surface squamous neoplasia in Xeroderma pigmentosum. Online Journal of Health and Allied Sciences, 12(3), [15].