TY - JOUR
T1 - Oncocytes in Mucoepidermoid Carcinoma of the Palate
T2 - Diagnostic Challenges
AU - Kumar, Rammohan
AU - Natarajan, Srikant
AU - Sneha, K. S.
AU - Chitra, Nunna Sai
AU - Boaz, Karen
AU - Manaktala, Nidhi
N1 - Publisher Copyright:
© 2017 Rammohan Kumar et al.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The origin of a salivary gland tumour is attributed to cells at various levels of differentiation which present histologically as diverse tissues and cellular patterns. Mitochondria-rich, eosinophilic oncocytes are cells commonly encountered in salivary gland neoplasms. We report a case of mucoepidermoid carcinoma (MEC) in the palate of a 43-year-old female that exhibited a prominent oncocytic component. While the parotid and submandibular glands have been reported as predominant sites for oncocytic MEC (OMEC), the palate and minor salivary glands are rare sites for occurrence. Also, most of the reported cases of OMEC have been histologically of low-grade mucoepidermoid carcinoma with large cystic spaces and good prognosis. In this article, we discuss the differential diagnosis and diagnostic workup of an MEC presenting with oncocytes.
AB - The origin of a salivary gland tumour is attributed to cells at various levels of differentiation which present histologically as diverse tissues and cellular patterns. Mitochondria-rich, eosinophilic oncocytes are cells commonly encountered in salivary gland neoplasms. We report a case of mucoepidermoid carcinoma (MEC) in the palate of a 43-year-old female that exhibited a prominent oncocytic component. While the parotid and submandibular glands have been reported as predominant sites for oncocytic MEC (OMEC), the palate and minor salivary glands are rare sites for occurrence. Also, most of the reported cases of OMEC have been histologically of low-grade mucoepidermoid carcinoma with large cystic spaces and good prognosis. In this article, we discuss the differential diagnosis and diagnostic workup of an MEC presenting with oncocytes.
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U2 - 10.1155/2017/5741821
DO - 10.1155/2017/5741821
M3 - Article
AN - SCOPUS:85042285538
SN - 2090-6447
VL - 2017
JO - Case Reports in Dentistry
JF - Case Reports in Dentistry
M1 - 5741821
ER -