Optic neuropathy induced by low dose of ethambutol: A rare presentation

Krishna Rao Addoor, Vuppalapati Nishant Janardhana Raju, Sulatha V. Bhandary, Sudha Girish Menon, Aakanksha Gupta

Research output: Contribution to journalArticle

Abstract

Ethambutol is a bacteriostatic antimicrobial agent used in the treatment of tuberculosis. Optic neuropathy is a potentially severe side effect of ethambutol, which is dose related. Ethambutol-induced optic neuropathy (EON) incidence is 15%, 5%, and 1% when taken at 50, 25, and 15 mg/kg/day, respectively, for 3 months. Hence, we report a case of bilateral EON in 20-year-old female after 1 month of exposure to 15 mg/kg/day of ethambutol for tubercular meningitis. Ophthalmologic examination revealed bilateral ill sustained pupillary reactions and optic disc pallor. Deranged color vision test and scotomas on Goldmann perimetry in both eyes, aided in diagnosis.

Original languageEnglish
Pages (from-to)12-13
Number of pages2
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue number4
DOIs
Publication statusPublished - 01-04-2017

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Pharmacology (medical)

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