Optical pathology of oral tissue

A raman spectroscopy diagnostic method

K. Venkatakrishna, Jacob Kurien, Keerthilatha M. Pai, Manna Valiathan, Nirmala Nagesh Kumar, C. Murali Krishna, G. Ullas, V. B. Kartha

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Raman and fluorescence spectroscopy methods are being considered as techniques which could be complementary or even alternative to biopsy, and pathology and clinical assays in many medical applications. The present paper discusses the results of Raman spectral studies on oral tissues for optical pathology. It is shown that Raman spectra of oral tissues can be classified into spectra of normal and malignant sets and a model based on such a classification can be used to analyse oral tissue for detection of oral malignancy. Sensitivity and specificity calculated from 90 test spectra are better than 85 and 90 per cent respectively.

Original languageEnglish
Pages (from-to)665-669
Number of pages5
JournalCurrent Science
Volume80
Issue number5
Publication statusPublished - 10-03-2001

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Oral Pathology
Raman Spectrum Analysis
Clinical Pathology
Fluorescence Spectrometry
Pathology
Biopsy
Sensitivity and Specificity
Neoplasms

All Science Journal Classification (ASJC) codes

  • General

Cite this

Venkatakrishna, K., Kurien, J., Pai, K. M., Valiathan, M., Kumar, N. N., Krishna, C. M., ... Kartha, V. B. (2001). Optical pathology of oral tissue: A raman spectroscopy diagnostic method. Current Science, 80(5), 665-669.
Venkatakrishna, K. ; Kurien, Jacob ; Pai, Keerthilatha M. ; Valiathan, Manna ; Kumar, Nirmala Nagesh ; Krishna, C. Murali ; Ullas, G. ; Kartha, V. B. / Optical pathology of oral tissue : A raman spectroscopy diagnostic method. In: Current Science. 2001 ; Vol. 80, No. 5. pp. 665-669.
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Venkatakrishna, K, Kurien, J, Pai, KM, Valiathan, M, Kumar, NN, Krishna, CM, Ullas, G & Kartha, VB 2001, 'Optical pathology of oral tissue: A raman spectroscopy diagnostic method', Current Science, vol. 80, no. 5, pp. 665-669.

Optical pathology of oral tissue : A raman spectroscopy diagnostic method. / Venkatakrishna, K.; Kurien, Jacob; Pai, Keerthilatha M.; Valiathan, Manna; Kumar, Nirmala Nagesh; Krishna, C. Murali; Ullas, G.; Kartha, V. B.

In: Current Science, Vol. 80, No. 5, 10.03.2001, p. 665-669.

Research output: Contribution to journalArticle

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AU - Pai, Keerthilatha M.

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Venkatakrishna K, Kurien J, Pai KM, Valiathan M, Kumar NN, Krishna CM et al. Optical pathology of oral tissue: A raman spectroscopy diagnostic method. Current Science. 2001 Mar 10;80(5):665-669.