Abstract

Background: Oral lesions have been reported to be the initial signs of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection. The main objective of the present study was to observe the prevalence of oral lesions among HIV/AIDS patients undergoing highly active antiretroviral therapy (HAART) attending the antiretroviral therapy (ART) center in Kasturba Medical College and Hospital, Mangalore, Dakshina Kannada, Karnataka, India. Materials and methods: One hundred and eight HIV/AIDS positive patients were evaluated by a single examiner. Patients’ oral cavity was examined and the various oral manifestations detected were recorded. Results: The most common extraoral manifestation was lipoatrophy, and intraorally, the most prevalent findings were intraoral pigmentation (42.6%) and candidiasis (27.8%). However, the prevalence of the most commonly associated lesions like Kaposi’s sarcoma (1.9%) and linear gingival erythema (2.7%) was less. Conclusion: Oral lesions are considered to be markers of progression of HIV into the final stage of AIDS. Advent of HAART has shown a significant reduction in the oral lesions and a better quality of life in patients with HIV.

Original languageEnglish
Pages (from-to)95-99
Number of pages5
JournalWorld Journal of Dentistry
Volume7
Issue number2
DOIs
Publication statusPublished - 01-04-2016

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Highly Active Antiretroviral Therapy
Acquired Immunodeficiency Syndrome
HIV
Oral Manifestations
Candidiasis
Kaposi's Sarcoma
Pigmentation
Erythema
Mouth
India
Quality of Life
Infection

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

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title = "Oral lesions in HIV/AIDS patients on highly active antiretroviral therapy",
abstract = "Background: Oral lesions have been reported to be the initial signs of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection. The main objective of the present study was to observe the prevalence of oral lesions among HIV/AIDS patients undergoing highly active antiretroviral therapy (HAART) attending the antiretroviral therapy (ART) center in Kasturba Medical College and Hospital, Mangalore, Dakshina Kannada, Karnataka, India. Materials and methods: One hundred and eight HIV/AIDS positive patients were evaluated by a single examiner. Patients’ oral cavity was examined and the various oral manifestations detected were recorded. Results: The most common extraoral manifestation was lipoatrophy, and intraorally, the most prevalent findings were intraoral pigmentation (42.6{\%}) and candidiasis (27.8{\%}). However, the prevalence of the most commonly associated lesions like Kaposi’s sarcoma (1.9{\%}) and linear gingival erythema (2.7{\%}) was less. Conclusion: Oral lesions are considered to be markers of progression of HIV into the final stage of AIDS. Advent of HAART has shown a significant reduction in the oral lesions and a better quality of life in patients with HIV.",
author = "Denny, {Ceena E.} and John Ramapuram and Bastian, {T. S.} and Ravikiran Ongole and Almas Binnal and Srikant Natarajan",
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Oral lesions in HIV/AIDS patients on highly active antiretroviral therapy. / Denny, Ceena E.; Ramapuram, John; Bastian, T. S.; Ongole, Ravikiran; Binnal, Almas; Natarajan, Srikant.

In: World Journal of Dentistry, Vol. 7, No. 2, 01.04.2016, p. 95-99.

Research output: Contribution to journalArticle

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T1 - Oral lesions in HIV/AIDS patients on highly active antiretroviral therapy

AU - Denny, Ceena E.

AU - Ramapuram, John

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AU - Binnal, Almas

AU - Natarajan, Srikant

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N2 - Background: Oral lesions have been reported to be the initial signs of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection. The main objective of the present study was to observe the prevalence of oral lesions among HIV/AIDS patients undergoing highly active antiretroviral therapy (HAART) attending the antiretroviral therapy (ART) center in Kasturba Medical College and Hospital, Mangalore, Dakshina Kannada, Karnataka, India. Materials and methods: One hundred and eight HIV/AIDS positive patients were evaluated by a single examiner. Patients’ oral cavity was examined and the various oral manifestations detected were recorded. Results: The most common extraoral manifestation was lipoatrophy, and intraorally, the most prevalent findings were intraoral pigmentation (42.6%) and candidiasis (27.8%). However, the prevalence of the most commonly associated lesions like Kaposi’s sarcoma (1.9%) and linear gingival erythema (2.7%) was less. Conclusion: Oral lesions are considered to be markers of progression of HIV into the final stage of AIDS. Advent of HAART has shown a significant reduction in the oral lesions and a better quality of life in patients with HIV.

AB - Background: Oral lesions have been reported to be the initial signs of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection. The main objective of the present study was to observe the prevalence of oral lesions among HIV/AIDS patients undergoing highly active antiretroviral therapy (HAART) attending the antiretroviral therapy (ART) center in Kasturba Medical College and Hospital, Mangalore, Dakshina Kannada, Karnataka, India. Materials and methods: One hundred and eight HIV/AIDS positive patients were evaluated by a single examiner. Patients’ oral cavity was examined and the various oral manifestations detected were recorded. Results: The most common extraoral manifestation was lipoatrophy, and intraorally, the most prevalent findings were intraoral pigmentation (42.6%) and candidiasis (27.8%). However, the prevalence of the most commonly associated lesions like Kaposi’s sarcoma (1.9%) and linear gingival erythema (2.7%) was less. Conclusion: Oral lesions are considered to be markers of progression of HIV into the final stage of AIDS. Advent of HAART has shown a significant reduction in the oral lesions and a better quality of life in patients with HIV.

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