Orbital melanocytoma

Alka Mary Mathai, Ramadas Naik, Muktha R. Pai, Jyoti R. Kini, Suneet Kumar, C. K. Ballal

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To report a case of intermediate grade meningeal melanocytoma presenting as a recurrent orbital mass. Introduction: Melanocytomas are rare, primary, pigmented tumors of the central nervous system, usually presenting as well-circumscribed, encapsulated, solid masses in the posterior cranial fossa and at the spinal region, often attached to the underlying dura. Orbital manifestation is rarely encountered. Methods: Case report with computed tomography scan, magnetic resonance imaging, histology, and immunohistochemistry. Results: A 40-year-old man presented with a recurrent orbital mass manifesting as progressive proptosis of the right eye of 4 years duration. The computed tomography scan and magnetic resonance imaging revealed an intraconal mass in the superior quadrant of the orbit. Histological analysis of the excision biopsy of the mass showed a highly cellular, locally infiltrating melanocytic neoplasm suggestive of an intermediate grade meningeal melanocytoma. Immunohistochemical staining for S-100 protein and HMB-45 monoclonal antibody confirmed the diagnosis. Conclusions: Recurrent intermediate grade orbital melanocytomas are rarely encountered and have to be distinguished from other topographically similar primary melanotic tumors. They have to be managed more aggressively if intracranial extension is present due to its close relation to the visual pathways.

Original languageEnglish
Pages (from-to)383-387
Number of pages5
JournalOrbit
Volume27
Issue number5
DOIs
Publication statusPublished - 01-09-2008

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Tomography
Magnetic Resonance Imaging
Posterior Cranial Fossa
Central Nervous System Neoplasms
Exophthalmos
Visual Pathways
S100 Proteins
Orbit
Neoplasms
Histology
Immunohistochemistry
Monoclonal Antibodies
Staining and Labeling
Biopsy

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Mathai, A. M., Naik, R., Pai, M. R., Kini, J. R., Kumar, S., & Ballal, C. K. (2008). Orbital melanocytoma. Orbit, 27(5), 383-387. https://doi.org/10.1080/01676830802333626
Mathai, Alka Mary ; Naik, Ramadas ; Pai, Muktha R. ; Kini, Jyoti R. ; Kumar, Suneet ; Ballal, C. K. / Orbital melanocytoma. In: Orbit. 2008 ; Vol. 27, No. 5. pp. 383-387.
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Mathai, AM, Naik, R, Pai, MR, Kini, JR, Kumar, S & Ballal, CK 2008, 'Orbital melanocytoma', Orbit, vol. 27, no. 5, pp. 383-387. https://doi.org/10.1080/01676830802333626

Orbital melanocytoma. / Mathai, Alka Mary; Naik, Ramadas; Pai, Muktha R.; Kini, Jyoti R.; Kumar, Suneet; Ballal, C. K.

In: Orbit, Vol. 27, No. 5, 01.09.2008, p. 383-387.

Research output: Contribution to journalArticle

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Mathai AM, Naik R, Pai MR, Kini JR, Kumar S, Ballal CK. Orbital melanocytoma. Orbit. 2008 Sep 1;27(5):383-387. https://doi.org/10.1080/01676830802333626