Oxidant-antioxidant status in colorectal cancer patients - Before and after treatment

Sharmila Upadhya; Subramanya Upadhya; S. Krishna Mohan; K. Vanajakshamma; Mamatha Kunder; Seema Mathias

doi:10.1007/BF02894261

Oxidant-antioxidant status in colorectal cancer patients - Before and after treatment

Sharmila Upadhya, Subramanya Upadhya, S. Krishna Mohan, K. Vanajakshamma, Mamatha Kunder, Seema Mathias

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Erythrocyte antioxidant glutathione and malondialdehyde levels in erythrocytes and plasma glutathione S-transferase levels were estimated in patients with colorectal cancer and compared to controls. Further, the patients underwent four weeks of radiotherapy with adjuvant chemotherapy. The same parameters were estimated after four weeks of radiotherapy and compared with pretreatment levels. It was observed that there was a decrease in erythrocyte glutathione and malondialdehyde levels in patients with colorectal cancer compared to controls, but not in case of GST. However, after chemoradiotherapy, there were no statistically significant differences in all the parameters studied.

Original language	English
Pages (from-to)	80-83
Number of pages	4
Journal	Indian Journal of Clinical Biochemistry
Volume	19
Issue number	2
DOIs	https://doi.org/10.1007/BF02894261
Publication status	Published - 01-01-2004
Externally published	Yes

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF02894261

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abstract = "Erythrocyte antioxidant glutathione and malondialdehyde levels in erythrocytes and plasma glutathione S-transferase levels were estimated in patients with colorectal cancer and compared to controls. Further, the patients underwent four weeks of radiotherapy with adjuvant chemotherapy. The same parameters were estimated after four weeks of radiotherapy and compared with pretreatment levels. It was observed that there was a decrease in erythrocyte glutathione and malondialdehyde levels in patients with colorectal cancer compared to controls, but not in case of GST. However, after chemoradiotherapy, there were no statistically significant differences in all the parameters studied.",

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AU - Upadhya, Sharmila

AU - Upadhya, Subramanya

AU - Mohan, S. Krishna

AU - Vanajakshamma, K.

AU - Kunder, Mamatha

AU - Mathias, Seema

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Erythrocyte antioxidant glutathione and malondialdehyde levels in erythrocytes and plasma glutathione S-transferase levels were estimated in patients with colorectal cancer and compared to controls. Further, the patients underwent four weeks of radiotherapy with adjuvant chemotherapy. The same parameters were estimated after four weeks of radiotherapy and compared with pretreatment levels. It was observed that there was a decrease in erythrocyte glutathione and malondialdehyde levels in patients with colorectal cancer compared to controls, but not in case of GST. However, after chemoradiotherapy, there were no statistically significant differences in all the parameters studied.

AB - Erythrocyte antioxidant glutathione and malondialdehyde levels in erythrocytes and plasma glutathione S-transferase levels were estimated in patients with colorectal cancer and compared to controls. Further, the patients underwent four weeks of radiotherapy with adjuvant chemotherapy. The same parameters were estimated after four weeks of radiotherapy and compared with pretreatment levels. It was observed that there was a decrease in erythrocyte glutathione and malondialdehyde levels in patients with colorectal cancer compared to controls, but not in case of GST. However, after chemoradiotherapy, there were no statistically significant differences in all the parameters studied.

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Oxidant-antioxidant status in colorectal cancer patients - Before and after treatment

Abstract

All Science Journal Classification (ASJC) codes

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