Oxidant status and antioxidant potential in diabetics

M. Nandini, K. Prasad, Nitha George, A. K. Rema, R. Prashanthi, K. Ashok Prabhu

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Abstract

The present study aimed at investigating the oxidative stress in persons with diabetes by estimating the plasma MDA (malondialdehyde) and erythrocyte susceptibility to peroxidation. Blood samples were obtained from 25 Type II diabetic patients who were attending the outpatient department of KMC Hospital, Ambedkar circle, Mangalore. The plasma glucose, MDA and erythrocyte susceptibility to peroxidation were measured in all the blood samples. Significant increase in plasma MDA along with glucose was evident in diabetics. However, the susceptibility of erythrocyte to peroxidation was not significantly different in diabetics as compared to the controls. Results of the present study indicate that though the oxidant status measured as malondialdehyde is increased in diabetes it does not disturb the erythrocyte antioxidant potential.

Original languageEnglish
Pages (from-to)97-99
Number of pages3
JournalBiomedical Research
Volume16
Issue number2
Publication statusPublished - 01-05-2005

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Nandini, M., Prasad, K., George, N., Rema, A. K., Prashanthi, R., & Ashok Prabhu, K. (2005). Oxidant status and antioxidant potential in diabetics. Biomedical Research, 16(2), 97-99.