Oxidation of L-leucine by alkaline diperiodatoargentate(III) deamination and decarboxylation

A kinetic and mechanistic study

Chanabasayya V. Hiremath, Suresh D. Kulkarni, Sharanappa T. Nandibewoor

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The oxidation of L-Leucine by alkaline diperiodatoargentate(III) (DPA) at 298 K and a constant ionic strength of 1.0 mol dm-3 was studied spectrophotometrically. The oxidation products are pentanoic acid and Ag (I). The stoichiometry is [L-Leucine]:[DPA] = 1:2. The reaction is of first order in [DPA] and has less than unit order in both [L-Leucine] and [alkali] and a retarding effect in [IO4-]. The oxidation reaction in alkaline medium has been shown to proceed via a L-Leucine-DPA complex, which further reacts with one molecule of DPA in a rate-determining step followed by other fast steps to give the products. The main products were identified by spot test and IR. The reaction constants involved in the different steps of the mechanism are calculated. The activation parameters with respect to the slow step of the mechanism are computed and discussed, and thermodynamic quantities are also determined. The probable active species of oxidation have been identified.

Original languageEnglish
Pages (from-to)8029-8035
Number of pages7
JournalIndustrial and Engineering Chemistry Research
Volume45
Issue number24
DOIs
Publication statusPublished - 22-11-2006

Fingerprint

decarboxylation
Leucine
oxidation
kinetics
Oxidation
Kinetics
Pentanoic Acids
Alkalies
stoichiometry
Ionic strength
Stoichiometry
Rate constants
thermodynamics
Chemical activation
Thermodynamics
Molecules
Acids
diperiodatoargentate(III)
Decarboxylation
acid

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Environmental Science(all)
  • Polymers and Plastics

Cite this

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abstract = "The oxidation of L-Leucine by alkaline diperiodatoargentate(III) (DPA) at 298 K and a constant ionic strength of 1.0 mol dm-3 was studied spectrophotometrically. The oxidation products are pentanoic acid and Ag (I). The stoichiometry is [L-Leucine]:[DPA] = 1:2. The reaction is of first order in [DPA] and has less than unit order in both [L-Leucine] and [alkali] and a retarding effect in [IO4-]. The oxidation reaction in alkaline medium has been shown to proceed via a L-Leucine-DPA complex, which further reacts with one molecule of DPA in a rate-determining step followed by other fast steps to give the products. The main products were identified by spot test and IR. The reaction constants involved in the different steps of the mechanism are calculated. The activation parameters with respect to the slow step of the mechanism are computed and discussed, and thermodynamic quantities are also determined. The probable active species of oxidation have been identified.",
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Oxidation of L-leucine by alkaline diperiodatoargentate(III) deamination and decarboxylation : A kinetic and mechanistic study. / Hiremath, Chanabasayya V.; Kulkarni, Suresh D.; Nandibewoor, Sharanappa T.

In: Industrial and Engineering Chemistry Research, Vol. 45, No. 24, 22.11.2006, p. 8029-8035.

Research output: Contribution to journalArticle

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N2 - The oxidation of L-Leucine by alkaline diperiodatoargentate(III) (DPA) at 298 K and a constant ionic strength of 1.0 mol dm-3 was studied spectrophotometrically. The oxidation products are pentanoic acid and Ag (I). The stoichiometry is [L-Leucine]:[DPA] = 1:2. The reaction is of first order in [DPA] and has less than unit order in both [L-Leucine] and [alkali] and a retarding effect in [IO4-]. The oxidation reaction in alkaline medium has been shown to proceed via a L-Leucine-DPA complex, which further reacts with one molecule of DPA in a rate-determining step followed by other fast steps to give the products. The main products were identified by spot test and IR. The reaction constants involved in the different steps of the mechanism are calculated. The activation parameters with respect to the slow step of the mechanism are computed and discussed, and thermodynamic quantities are also determined. The probable active species of oxidation have been identified.

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