Oxidative stress and low dose ionizing radiation

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15 Citations (Scopus)

Abstract

The field of radiation biochemistry has provided tremendous impact in recent years as extensive research on free radicals has implicated them in radiation damage. An important offshoot of this field is the branch dealing with radiological protection in medical applications like diagnostic radiology. Hence, we decided to investigate the relationship between oxidative stress and low dose ionizing radiation (x-rays) in the work environment of x-ray technicians (radiographers), by comparing their RBC malondialdehyde, % hemolysis, catalase and plasma vitamin E levels with those of controls. There was a significant increase in the susceptibility of RBCs to hemolysis in radiographers compared to controls. Malondialdehyde and catalase levels were slightly increased in the radiographers, but this did not disturb the steady state concentration of their plasma vitamin E. These findings go in favour of theories stating that exposure to low dose ionizing radiation does cause a greater amount of oxidative stress, than that caused during normal routine metabolic processes.

Original languageEnglish
Pages (from-to)181-184
Number of pages4
JournalIndian Journal of Physiology and Pharmacology
Volume53
Issue number2
Publication statusPublished - 01-04-2009

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology
  • Physiology (medical)

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