Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

L.A. Saldanha, G. Elias, M.N.A. Rao

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.
Original languageUndefined/Unknown
Pages (from-to)89-91
Number of pages3
JournalArzneimittel-Forschung/Drug Research
Volume40
Issue number1
Publication statusPublished - 1990

Cite this

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title = "Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity",
abstract = "A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.",
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Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity. / Saldanha, L.A.; Elias, G.; Rao, M.N.A.

In: Arzneimittel-Forschung/Drug Research, Vol. 40, No. 1, 1990, p. 89-91.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

AU - Saldanha, L.A.

AU - Elias, G.

AU - Rao, M.N.A.

N1 - cited By 47

PY - 1990

Y1 - 1990

N2 - A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.

AB - A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.

M3 - Article

VL - 40

SP - 89

EP - 91

JO - Drug Research

JF - Drug Research

SN - 2194-9379

IS - 1

ER -