Oxygen radiacl scavenging activity of phenylbutenones and their correlation with antiinflammatory activity

L.A. Saldanha, G. Elias, M.N.A. Rao

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Abstract

A number of ring substituted (E-)-4-phenyl-3-buten-2-ones including dehydrozingerone were studied for their oxygen radical scavenging properties. They scavenged superoxide and hydroxyl radicals to an appreciable extent. Good correlation (r = 0.87) was obtained between superoxide scavenging and antiinflammatory activity. The correlation was not significant with the hydroxyl scavenging activity.
Original languageUndefined/Unknown
Pages (from-to)89-91
Number of pages3
JournalArzneimittel-Forschung/Drug Research
Volume40
Issue number1
Publication statusPublished - 1990

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