Postpartum hemorrhage remains the leading cause of maternal mortality and morbidity. Oxytocic drugs are the main stay in prevention as well as treatment. Oxytocin remains the drug of choice. The use of 5 IU bolus dose has been questioned in recent times. Current evidence suggests infusion to be a preferred choice than bolus dosage. Carbetocin is a newer alternative to oxytocin. Second line drugs include ergot alkaloids (Methyl ergometrine) and prostaglandins (carboprost and misoprostol) which are used as adjuvants to oxytocin in hemorrhage.
All Science Journal Classification (ASJC) codes
- Anesthesiology and Pain Medicine