Paper and thread as media for the frugal detection of urinary tract infections (UTIs)

Amrutha Hasandka, Ankita Ramchandran Singh, Anusha Prabhu, Hardik Ramesh Singhal, M. S.Giri Nandagopal, Naresh Kumar Mani

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)

Abstract

Urinary tract infections (UTIs) make up a significant proportion of the global burden of disease in vulnerable groups and tend to substantially impair the quality of life of those affected, making timely detection of UTIs a priority for public health. However, economic and societal barriers drastically reduce accessibility of traditional lab-based testing methods for critical patient groups in low-resource areas, negatively affecting their overall healthcare outcomes. As a result, cellulose-based materials such as paper and thread have garnered significant interest among researchers as substrates for so-called frugal analytical devices which leverage the material’s portability and adaptability for facile and reproducible diagnoses of UTIs. Although the field may be only in its infancy, strategies aimed at commercial penetration can appreciably increase access to more healthcare options for at-risk people. In this review, we catalogue recent advances in devices that use cellulose-based materials as the primary housing or medium for UTI detection and chart out trends in the field. We also explore different modalities employed for detection, with particular emphasis on their ability to be ported onto discreet casings such as sanitary products. Graphical abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)847-865
Number of pages19
JournalAnalytical and Bioanalytical Chemistry
Volume414
Issue number2
DOIs
Publication statusPublished - 01-2022

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry

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