Papillary glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

Aparna Govindan, Anita Mahadevan, D. I. Bhat, A. Arivazhagan, Shrijeet Chakraborti, M. S. Suja, A. A. Phalguni, S. Sampath, B. A. Chandramouli, S. K. Shankar

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Abstract

Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.

Original languageEnglish
Pages (from-to)71-80
Number of pages10
JournalJournal of Neuro-Oncology
Volume95
Issue number1
DOIs
Publication statusPublished - 30-04-2009

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All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cancer Research
  • Oncology
  • Neurology

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